Mahsa Rezvan, Seyed Erfan Hossini, Kimia Sarmast, Faham Khamesipour
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The Efficiency of Plant Extracts in the Prevention of Gastric Cancer: A Systematic Review
Background and Aims
Gastric cancer is a global health concern with high morbidity and mortality. This systematic review evaluates the potential of plant extracts in the prevention of gastric cancer by analyzing their bioactive mechanisms.
Methods
A total of 62 studies—including in vitro, in vivo, and clinical trials—were analyzed, focusing on their antiproliferative, proapoptotic, antiangiogenic, and anti-inflammatory properties.
Results
Extracts such as Marsdenia tenacissima, Curcuma longa, and Rhus verniciflua showed significant promise.
Conclusion
Despite these findings, issues surrounding bioavailability, dosing standardization, and long-term safety require further investigation before clinical translation.