昼夜节律失调作为失眠严重程度的决定因素：在睡眠医学临床实践中的可能含义

IF 6.3 1区医学 Q1 ENDOCRINOLOGY & METABOLISM

Journal of Pineal Research Pub Date : 2025-09-21 DOI:10.1111/jpi.70085

Alessandro Colitta, Ugo Faraguna

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引用次数: 0

摘要

在这封致编辑的信中，我们对Scott等人（2025）最近发表的研究进行了评论，该研究强调昼夜节律失调可能是失眠严重程度的决定因素。考虑到这项研究的强大方法，以及最近旨在优化褪黑激素治疗方案的研究，我们的信探讨了为什么这些发现可能为延长目前对失眠褪黑激素治疗的建议铺平道路，同时鼓励在睡眠医学临床实践中量化昼夜节律失调。最后，讨论了常规评估失眠患者昼夜节律失调的可能方法。

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Circadian Misalignment as a Determinant of Insomnia Severity: Possible Implications in Sleep Medicine Clinical Practice

In this letter to the editor, we comment on the recently published study from Scott et al. (2025), which highlights circadian misalignment as a possible determinant of insomnia severity. Considering the robust methodology of this study and in light of recent research aiming at optimizing melatonin treatment schedules, our letter explores why these findings may pave the way towards an extension of current recommendations for melatonin administration in insomnia, while encouraging the quantification of circadian misalignment during sleep medicine clinical practice. Finally, possible methodologies to routinely assess circadian misalignment in insomnia patients are discussed.

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来源期刊

Journal of Pineal Research 医学-内分泌学与代谢

CiteScore

17.70

自引率

4.90%

发文量

审稿时长

1 months

期刊介绍： The Journal of Pineal Research welcomes original scientific research on the pineal gland and melatonin in vertebrates, as well as the biological functions of melatonin in non-vertebrates, plants, and microorganisms. Criteria for publication include scientific importance, novelty, timeliness, and clarity of presentation. The journal considers experimental data that challenge current thinking and welcomes case reports contributing to understanding the pineal gland and melatonin research. Its aim is to serve researchers in all disciplines related to the pineal gland and melatonin.