{"title":"猫白血病病毒亚群使用病毒干扰试验","authors":"Dimas Arya Abdillah, Takahiro Hiratsuka, Fumiko Matsuyama, Yuki Hattori, Takehisa Soma, Tetsuya Shimoda, Takashi Kato, Hideo Sakai, Masaharu Hisasue, Ariko Miyake, Kazuo Nishigaki","doi":"10.1007/s00705-025-06407-1","DOIUrl":null,"url":null,"abstract":"<div><p>Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated <i>de novo</i>. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.</p></div>","PeriodicalId":8359,"journal":{"name":"Archives of Virology","volume":"170 10","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Feline leukaemia virus subgrouping using a viral interference assay\",\"authors\":\"Dimas Arya Abdillah, Takahiro Hiratsuka, Fumiko Matsuyama, Yuki Hattori, Takehisa Soma, Tetsuya Shimoda, Takashi Kato, Hideo Sakai, Masaharu Hisasue, Ariko Miyake, Kazuo Nishigaki\",\"doi\":\"10.1007/s00705-025-06407-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated <i>de novo</i>. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.</p></div>\",\"PeriodicalId\":8359,\"journal\":{\"name\":\"Archives of Virology\",\"volume\":\"170 10\",\"pages\":\"\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Virology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00705-025-06407-1\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Virology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00705-025-06407-1","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VIROLOGY","Score":null,"Total":0}
Feline leukaemia virus subgrouping using a viral interference assay
Feline leukaemia virus subgroup A (FeLV-A) is transmitted among cats, and FeLV subgroups are frequently generated de novo. We investigated the frequency of detection of subgroups using interference assays in 50 cases. FeLV-A infection alone was detected in 38% of the cases, whereas coinfection with both FeLV-A and FeLV-B was observed in 62% of the cases. No cases of FeLV-B infection alone were observed. Cases of coinfection with FeLV-A and FeLV-B showed a higher prevalence than cases of FeLV-A infection alone. The FeLV containing an X region was discovered in two new cases. This study may help to elucidate the mechanism underlying FeLV-B-associated diseases.
期刊介绍:
Archives of Virology publishes original contributions from all branches of research on viruses, virus-like agents, and virus infections of humans, animals, plants, insects, and bacteria. Coverage spans a broad spectrum of topics, from descriptions of newly discovered viruses, to studies of virus structure, composition, and genetics, to studies of virus interactions with host cells, organisms and populations. Studies employ molecular biologic, molecular genetics, and current immunologic and epidemiologic approaches. Contents include studies on the molecular pathogenesis, pathophysiology, and genetics of virus infections in individual hosts, and studies on the molecular epidemiology of virus infections in populations. Also included are studies involving applied research such as diagnostic technology development, monoclonal antibody panel development, vaccine development, and antiviral drug development.Archives of Virology wishes to publish obituaries of recently deceased well-known virologists and leading figures in virology.