光诱导铜催化环肟酯自由基开环叠氮化反应

IF 4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-09-22 DOI:10.1002/adsc.70133

Li-Bo Yang, Jia Hu, Tian-Tian Zou, Xin-Song Zhou, Jing Li, Yuan Qu, Ya-Min Li

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引用次数: 0

摘要

采用光诱导铜催化环肟酯自由基开环叠氮化反应，合成了有价γ-叠氮基烷基腈。此外，成功地实现了一锅序贯策略，将开环叠氮化与铜催化叠氮化-炔环加成相结合，实现了在一次操作中直接构建1,2,3-三唑衍生物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Photoinduced Copper-Catalyzed Radical Ring-Opening Azidation of Cyclic Oxime Esters

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Photoinduced Copper-Catalyzed Radical Ring-Opening Azidation of Cyclic Oxime Esters

A photoinduced copper-catalyzed radical ring-opening azidation of cyclic oxime esters has been developed for the synthesis of valuable γ-azido alkylnitriles. Furthermore, a one-pot sequential strategy integrating this ring-opening azidation with copper-catalyzed azide–alkyne cycloaddition is successfully implemented, enabling the direct construction of 1,2,3-triazole derivatives in a single operation.

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.