Suppressing quantum errors by noise-aware circuit design

Suppressing errors is one of the central challenges in achieving reliable quantum computation on near-term hardware. While much attention has been paid to error correction and mitigation, we identify quantum circuit structure itself as a powerful lever for proactive error suppression. In this work, we present a unified and hardware-adaptive framework for noise-aware quantum circuit design, in which circuit topology and parameters are co-optimized from the ground up based on the noise profile of the target backend. Our framework supports a wide range of quantum tasks-including circuit compilation, quantum state preparation, and unitary approximation-under a consistent optimization paradigm. Extensive experiments on five IBM backends confirm the effectiveness of our method, showing significant fidelity gains across all tasks under realistic noise. These results demonstrate that noise suppression through structure-aware design offers a powerful and generalizable strategy for enhancing circuit performance on NISQ hardware. Our framework bridges low-level hardware constraints with high-level circuit synthesis, paving the way for more robust and efficient quantum programming in the presence of noise.