免疫功能正常的老年慢性阻塞性肺疾病患者合并中耳诺卡菌和结核分枝杆菌感染：北印度一例罕见病例。

Q3 Medicine

Indian Journal of Tuberculosis Pub Date : 2025-01-11 DOI:10.1016/j.ijtb.2025.01.002

Khutheibam Khalida Fazli , Jaweed Ahmed , Vikas Saini , Roumi Ghosh , Sangita Gupta , Deepti Rawat , Sonia Malik

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引用次数: 0

摘要

慢性阻塞性肺疾病（COPD）患者由于长期或间歇性局部使用皮质类固醇，其结构和免疫防御机制受到损害，易发生各种细菌和病毒性呼吸道感染。慢性阻塞性肺病是结核分枝杆菌（MTB）和诺卡菌属（Nocardia spp）的常见易感因素。在此，我们报告一例75岁患有慢性阻塞性肺病的男性诺卡菌病和肺结核（PTB）合并感染。耳根诺卡菌引起的感染仍然很少报道。同时伴有诺卡菌病的肺结核可能有毁灭性的后果，并可能被忽视。因此，在结核病和诺卡菌病中，早期诊断和开始治疗至关重要。

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Co-infection of Nocardia otitidiscaviarum and Mycobacterium tuberculosis in an immunocompetent elderly patient with chronic obstructive pulmonary disease: A rare case from North India

Chronic obstructive pulmonary disease (COPD) patients are susceptible to various bacterial and viral respiratory infections due to jeopardized structural and immunological defense mechanism along with long term or intermittent local corticosteroid administration. COPD is a common susceptibility factor for both Mycobacterium tuberculosis (MTB) and Nocardia spp. Herein, we report a case of co-infection of pulmonary nocardiosis and pulmonary tuberculosis (PTB) in a 75-year-old man with COPD. Infections due to Nocardia otitidiscaviarum remain infrequently reported. Concurrent PTB with nocardiosis may have devastating outcomes and may be missed. Hence, early diagnosis and initiation of therapy are crucial in both Tuberculosis and Nocardiosis.

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来源期刊

Indian Journal of Tuberculosis Medicine-Infectious Diseases

CiteScore

2.80

自引率

0.00%

发文量

103

期刊介绍： Indian Journal of Tuberculosis (IJTB) is an international peer-reviewed journal devoted to the specialty of tuberculosis and lung diseases and is published quarterly. IJTB publishes research on clinical, epidemiological, public health and social aspects of tuberculosis. The journal accepts original research articles, viewpoints, review articles, success stories, interesting case series and case reports on patients suffering from pulmonary, extra-pulmonary tuberculosis as well as other respiratory diseases, Radiology Forum, Short Communications, Book Reviews, abstracts, letters to the editor, editorials on topics of current interest etc. The articles published in IJTB are a key source of information on research in tuberculosis. The journal is indexed in Medline