封面：用于光标记活细胞中生物分子的光活化炔标签（ChemBioChem 17/2025）

IF 2.8 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

ChemBioChem Pub Date : 2025-09-17 DOI:10.1002/cbic.70018

Yuki Umeda, Hao Zhu, Satoshi Yamaguchi, Sho Nakamura, Masato Takada, Shin Izuta, Akimitsu Okamoto

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引用次数: 0

摘要

封面展示了一种新开发的光激活突出“服装”，突出了细胞内生物系统拥挤舞台上的关键分子。在研究文章（DOI: 10.1002/cbic）。202500190), Satoshi Yamaguchi， Akimitsu Okamoto及其同事描述了他们如何基于Echenmoser-Tanabe反应的光固化中间体设计了一种可光激活的标签，该标签可以在光照射下在细胞内转化为末端线性烷基，作为分子成像的可激活探针。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Front Cover: Photoactivatable Alkyne Tag for Photolabeling Biomolecules in Living Cells (ChemBioChem 17/2025)

查看原文本刊更多论文

Front Cover: Photoactivatable Alkyne Tag for Photolabeling Biomolecules in Living Cells (ChemBioChem 17/2025)

The Cover shows a newly developed photoactivatable standout “costume” that highlights key molecules on the crowded stage of intracellular biosystems. In the Research Article (DOI: 10.1002/cbic.202500190), Satoshi Yamaguchi, Akimitsu Okamoto, and co-workers describe how they designed a light-activatable tag based on a photocaged intermediate of the Echenmoser–Tanabe reaction, which can be converted into a terminal linear alkyne within cells upon light irradiation, serving as an activatable probe for molecular imaging.

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来源期刊

ChemBioChem 生物-生化与分子生物学

CiteScore

6.10

自引率

3.10%

发文量

407

审稿时长

1 months

期刊介绍： ChemBioChem (Impact Factor 2018: 2.641) publishes important breakthroughs across all areas at the interface of chemistry and biology, including the fields of chemical biology, bioorganic chemistry, bioinorganic chemistry, synthetic biology, biocatalysis, bionanotechnology, and biomaterials. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and supported by the Asian Chemical Editorial Society (ACES).