心内膜炎的一个被忽视的病因——大细静脉炎1例报告

IF 2.6 3区 生物学 Q3 MICROBIOLOGY
Charlie Zins , Loic Biere , Mohamed Braham , Rachel Chenouard , Matthieu Eveillard , Marie Kempf , Vincent Dubée , Hélène Pailhoriès
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引用次数: 0

摘要

大心内膜炎是一种罕见且诊断不足的疾病,主要影响人工瓣膜。我们报告了一个病例,并进行了全面的文献回顾,强调其亚急性的表现和诊断的挑战,由于频繁的阴性血培养。分子检测方法和长时间的厌氧培养是鉴定F. magna的关键。考虑到瓣膜损伤的高风险,包括脓肿的形成,可能需要手术干预。文献中的抗生素治疗包括青霉素,加或不加甲硝唑。临床医生应该考虑这种被低估的病原体作为早期人工瓣膜心内膜炎的潜在原因,特别是在无菌血液培养的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Finegoldia magna, a neglected cause of endocarditis – case report
Finegoldia magna endocarditis is a rare and underdiagnosed condition, primarily affecting prosthetic valves. We report a case, along with a comprehensive literature review, highlighting its subacute presentation and the challenges in diagnosis due to frequent negative blood cultures. Molecular detection methods and prolonged delay for anaerobic cultures are crucial for identifying F. magna. Given the high risk of significant valvular damage, including abscess formation, surgical intervention might be required. Antibiotic treatments in the literature include penicillins, with or without metronidazole. Clinicians should consider this underestimated pathogen as a potential cause of early prosthetic valve endocarditis, particularly in cases of sterile blood cultures.
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来源期刊
Anaerobe
Anaerobe 生物-微生物学
CiteScore
5.20
自引率
8.70%
发文量
137
审稿时长
76 days
期刊介绍: Anaerobe is essential reading for those who wish to remain at the forefront of discoveries relating to life processes of strictly anaerobes. The journal is multi-disciplinary, and provides a unique forum for those investigating anaerobic organisms that cause infections in humans and animals, as well as anaerobes that play roles in microbiomes or environmental processes. Anaerobe publishes reviews, mini reviews, original research articles, notes and case reports. Relevant topics fall into the broad categories of anaerobes in human and animal diseases, anaerobes in the microbiome, anaerobes in the environment, diagnosis of anaerobes in clinical microbiology laboratories, molecular biology, genetics, pathogenesis, toxins and antibiotic susceptibility of anaerobic bacteria.
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