Vanessa Defelícibus, Leticia Philippi, Victória Maes, Ana Paula Anzolin
{"title":"臭氧治疗面部协调并发症2例报告","authors":"Vanessa Defelícibus, Leticia Philippi, Victória Maes, Ana Paula Anzolin","doi":"10.1016/j.hmedic.2025.100371","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Facial harmonization procedures, while popular, can lead to complications such as persistent edema, nodules, and scarring with retraction. Ozone therapy, known for its anti-inflammatory, oxygenating, and regenerative properties, has emerged as a potential adjuvant treatment to improve clinical outcomes in such cases.</div></div><div><h3>Case reports</h3><div>Case 1 involved a 42-year-old female patient who developed persistent facial edema and nodules following an inappropriate hyaluronic acid application. Treatment included ultrasound-guided hyaluronidase injections and subcutaneous medical ozone therapy, resulting in a progressive reduction of inflammation and improved facial symmetry. Case 2 described a 48-year-old female patient with severe scar retraction of the lower eyelids after a \"non-surgical blepharoplasty\" using a plasma jet, leading to ectropion and ocular pain. Management combined subcutaneous ozone therapy, cyclic eyelid traction, and reconstructive surgery, achieving symptom relief, functional recovery, and anatomical stability.</div></div><div><h3>Conclusion</h3><div>Ozone therapy demonstrated a significant adjuvant role in managing complications from facial aesthetic procedures by modulating inflammation, enhancing tissue oxygenation, and promoting local tissue regeneration, ultimately contributing to improved clinical outcomes.</div></div>","PeriodicalId":100908,"journal":{"name":"Medical Reports","volume":"14 ","pages":"Article 100371"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Integrated management of facial harmonization complications using ozone therapy: A description of 2 cases\",\"authors\":\"Vanessa Defelícibus, Leticia Philippi, Victória Maes, Ana Paula Anzolin\",\"doi\":\"10.1016/j.hmedic.2025.100371\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Facial harmonization procedures, while popular, can lead to complications such as persistent edema, nodules, and scarring with retraction. Ozone therapy, known for its anti-inflammatory, oxygenating, and regenerative properties, has emerged as a potential adjuvant treatment to improve clinical outcomes in such cases.</div></div><div><h3>Case reports</h3><div>Case 1 involved a 42-year-old female patient who developed persistent facial edema and nodules following an inappropriate hyaluronic acid application. Treatment included ultrasound-guided hyaluronidase injections and subcutaneous medical ozone therapy, resulting in a progressive reduction of inflammation and improved facial symmetry. Case 2 described a 48-year-old female patient with severe scar retraction of the lower eyelids after a \\\"non-surgical blepharoplasty\\\" using a plasma jet, leading to ectropion and ocular pain. Management combined subcutaneous ozone therapy, cyclic eyelid traction, and reconstructive surgery, achieving symptom relief, functional recovery, and anatomical stability.</div></div><div><h3>Conclusion</h3><div>Ozone therapy demonstrated a significant adjuvant role in managing complications from facial aesthetic procedures by modulating inflammation, enhancing tissue oxygenation, and promoting local tissue regeneration, ultimately contributing to improved clinical outcomes.</div></div>\",\"PeriodicalId\":100908,\"journal\":{\"name\":\"Medical Reports\",\"volume\":\"14 \",\"pages\":\"Article 100371\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949918625002165\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949918625002165","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Integrated management of facial harmonization complications using ozone therapy: A description of 2 cases
Background
Facial harmonization procedures, while popular, can lead to complications such as persistent edema, nodules, and scarring with retraction. Ozone therapy, known for its anti-inflammatory, oxygenating, and regenerative properties, has emerged as a potential adjuvant treatment to improve clinical outcomes in such cases.
Case reports
Case 1 involved a 42-year-old female patient who developed persistent facial edema and nodules following an inappropriate hyaluronic acid application. Treatment included ultrasound-guided hyaluronidase injections and subcutaneous medical ozone therapy, resulting in a progressive reduction of inflammation and improved facial symmetry. Case 2 described a 48-year-old female patient with severe scar retraction of the lower eyelids after a "non-surgical blepharoplasty" using a plasma jet, leading to ectropion and ocular pain. Management combined subcutaneous ozone therapy, cyclic eyelid traction, and reconstructive surgery, achieving symptom relief, functional recovery, and anatomical stability.
Conclusion
Ozone therapy demonstrated a significant adjuvant role in managing complications from facial aesthetic procedures by modulating inflammation, enhancing tissue oxygenation, and promoting local tissue regeneration, ultimately contributing to improved clinical outcomes.