水培南瓜中四氯双酚A的脱氯和甲基化。

IF 2.8 4区环境科学与生态学 Q2 ENVIRONMENTAL SCIENCES

Environmental Toxicology and Chemistry Pub Date : 2025-09-18 DOI:10.1093/etojnl/vgaf233

Ying Li, Yonglin Liu, Huiru Qiu, Weiliang Wang, Xiaoxuan Han, Weihao Xu, Lin Liu, Zhenxue Dai, Yong Tian

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引用次数: 0

摘要

四氯双酚A （TCBPA）是一种广泛使用的经济型阻燃剂，在环境中检测频率较高。然而，其在模式生物中的生物积累和代谢尚不清楚。本研究采用水培法将南瓜植株暴露于TCBPA中，以探索其代谢行为。结果表明，TCBPA的吸收分布在植株的各个部位，其中根的吸收量最高（1860±63 ng），其次是茎（99.6±10.9 ng）和叶（11.8±0.9 ng）。TCBPA从水培液中被根吸收，随后转移到茎和叶中。在根（3.35±0.87 ng）和茎（0.201±0.018 ng）中检测到TCBPA脱氯产物Tri-CBPA，在根（122±14 ng）和茎（2.03±0.27 ng）中检测到TCBPA甲基化产物TCBPA- mme。预测TCBPA代谢物毒性低于TCBPA，表明南瓜植物在TCBPA污染修复中的潜在用途。该研究结果阐明了TCBPA在模式生物（即南瓜植物）中的吸收、迁移和转化。

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Dechlorination and Methylation of Tetrachlorobisphenol A in Hydroponic Pumpkin.

Tetrachlorobisphenol A (TCBPA) is widely used as an economical flame retardant and frequently detected in the environment. However, its bioaccumulation and metabolism in model organisms are unknown. Herein, pumpkin plants were hydroponically exposed to TCBPA to explore its metabolic behavior. The results indicated that TCBPA was absorbed and distributed throughout the plant, with the highest amount found in the roots (1860 ± 63 ng), followed by the stem (99.6 ± 10.9 ng) and leaves (11.8 ± 0.9 ng). TCBPA was absorbed by the roots from the hydroponic solution, subsequently translocated to the stem and leaves. The dechlorination product of TCBPA, Tri-CBPA, was detected in the roots (3.35 ± 0.87 ng) and stem (0.201 ± 0.018 ng), and its methylation product, TCBPA-MME, was also identified in the roots (122 ± 14 ng) and stem (2.03 ± 0.27 ng). TCBPA metabolites were predicted to be less toxic than TCBPA, indicating the potential use of pumpkin plants in TCBPA pollution remediation. The study findings clarify the absorption, migration, and transformation of TCBPA in a model organism, ie, pumpkin plants.

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来源期刊

Environmental Toxicology and Chemistry 环境科学-毒理学

CiteScore

7.40

自引率

9.80%

发文量

265

审稿时长

3.4 months

期刊介绍： The Society of Environmental Toxicology and Chemistry (SETAC) publishes two journals: Environmental Toxicology and Chemistry (ET&C) and Integrated Environmental Assessment and Management (IEAM). Environmental Toxicology and Chemistry is dedicated to furthering scientific knowledge and disseminating information on environmental toxicology and chemistry, including the application of these sciences to risk assessment.[...] Environmental Toxicology and Chemistry is interdisciplinary in scope and integrates the fields of environmental toxicology; environmental, analytical, and molecular chemistry; ecology; physiology; biochemistry; microbiology; genetics; genomics; environmental engineering; chemical, environmental, and biological modeling; epidemiology; and earth sciences. ET&C seeks to publish papers describing original experimental or theoretical work that significantly advances understanding in the area of environmental toxicology, environmental chemistry and hazard/risk assessment. Emphasis is given to papers that enhance capabilities for the prediction, measurement, and assessment of the fate and effects of chemicals in the environment, rather than simply providing additional data. The scientific impact of papers is judged in terms of the breadth and depth of the findings and the expected influence on existing or future scientific practice. Methodological papers must make clear not only how the work differs from existing practice, but the significance of these differences to the field. Site-based research or monitoring must have regional or global implications beyond the particular site, such as evaluating processes, mechanisms, or theory under a natural environmental setting.