{"title":"2012 - 2022年金沙萨大学诊所非霍奇金淋巴瘤流行病学分析","authors":"Mbwamulungu Nakweti Julia, Azako David, Pezo Serge, Bokambadja Fabrice, Kapour Kieng Germain, Bompangue Nkoko Didier, Kisile Olive, Lebwaze Massamba Bienvenu, Kabongo Mpolesha Jean-Marie","doi":"10.1002/cam4.71254","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p>Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years. In the DRC, the absence of a national cancer registry is a serious handicap to the epidemiological evaluation of NHL. There is still a lack of knowledge about this pathology among the population and health professionals. An observational survey of the country's hospitals is enough to note the absence of protocols for the management of NHL. The objective of this study is to determine the epidemiological aspects of non-Hodgkin lymphoma in the DRC.</p>\n </section>\n \n <section>\n \n <h3> Materials and Methods</h3>\n \n <p>A descriptive cross-sectional study, conducted at the University Clinics of Kinshasa, from 2012 to 2022. The chi-square correlation test is used to compare proportions with the 95% confidence interval (<i>α</i> = 0.05).</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Out of a total of 2070 cancer cases, 51 NHL cases were recorded, or 2.5%. 98% of the recorded cases were B-cell lymphomas compared to 2% T-cell lymphomas. 80% of cases were aggressive and 20% were indolent. 55% of cases were male versus 45% female, with a sex ratio of 1.2. The age of the patients ranged from 3 to 80 years, with a mean age of 42 years and a median of 45 years. The histological type DLBCL was predominant in 63% of cases. 59% of cases involved lymph nodes.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years, with the outbreak of environmental and infectious factors. Knowledge of epidemiological aspects contributes to the improvement of the fight against NHL in the DRC.</p>\n </section>\n </div>","PeriodicalId":139,"journal":{"name":"Cancer Medicine","volume":"14 18","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.71254","citationCount":"0","resultStr":"{\"title\":\"Epidemiological Profile of Non-Hodgkin's Lymphomas Seen at Kinshasa University Clinics From 2012 to 2022\",\"authors\":\"Mbwamulungu Nakweti Julia, Azako David, Pezo Serge, Bokambadja Fabrice, Kapour Kieng Germain, Bompangue Nkoko Didier, Kisile Olive, Lebwaze Massamba Bienvenu, Kabongo Mpolesha Jean-Marie\",\"doi\":\"10.1002/cam4.71254\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Introduction</h3>\\n \\n <p>Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years. In the DRC, the absence of a national cancer registry is a serious handicap to the epidemiological evaluation of NHL. There is still a lack of knowledge about this pathology among the population and health professionals. An observational survey of the country's hospitals is enough to note the absence of protocols for the management of NHL. The objective of this study is to determine the epidemiological aspects of non-Hodgkin lymphoma in the DRC.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Materials and Methods</h3>\\n \\n <p>A descriptive cross-sectional study, conducted at the University Clinics of Kinshasa, from 2012 to 2022. The chi-square correlation test is used to compare proportions with the 95% confidence interval (<i>α</i> = 0.05).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Out of a total of 2070 cancer cases, 51 NHL cases were recorded, or 2.5%. 98% of the recorded cases were B-cell lymphomas compared to 2% T-cell lymphomas. 80% of cases were aggressive and 20% were indolent. 55% of cases were male versus 45% female, with a sex ratio of 1.2. The age of the patients ranged from 3 to 80 years, with a mean age of 42 years and a median of 45 years. The histological type DLBCL was predominant in 63% of cases. 59% of cases involved lymph nodes.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years, with the outbreak of environmental and infectious factors. Knowledge of epidemiological aspects contributes to the improvement of the fight against NHL in the DRC.</p>\\n </section>\\n </div>\",\"PeriodicalId\":139,\"journal\":{\"name\":\"Cancer Medicine\",\"volume\":\"14 18\",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cam4.71254\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cancer Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71254\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Medicine","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cam4.71254","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Epidemiological Profile of Non-Hodgkin's Lymphomas Seen at Kinshasa University Clinics From 2012 to 2022
Introduction
Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years. In the DRC, the absence of a national cancer registry is a serious handicap to the epidemiological evaluation of NHL. There is still a lack of knowledge about this pathology among the population and health professionals. An observational survey of the country's hospitals is enough to note the absence of protocols for the management of NHL. The objective of this study is to determine the epidemiological aspects of non-Hodgkin lymphoma in the DRC.
Materials and Methods
A descriptive cross-sectional study, conducted at the University Clinics of Kinshasa, from 2012 to 2022. The chi-square correlation test is used to compare proportions with the 95% confidence interval (α = 0.05).
Results
Out of a total of 2070 cancer cases, 51 NHL cases were recorded, or 2.5%. 98% of the recorded cases were B-cell lymphomas compared to 2% T-cell lymphomas. 80% of cases were aggressive and 20% were indolent. 55% of cases were male versus 45% female, with a sex ratio of 1.2. The age of the patients ranged from 3 to 80 years, with a mean age of 42 years and a median of 45 years. The histological type DLBCL was predominant in 63% of cases. 59% of cases involved lymph nodes.
Conclusion
Non-Hodgkin lymphoma (NHL) is a heterogeneous group of cancers whose global incidence has been increasing in recent years, with the outbreak of environmental and infectious factors. Knowledge of epidemiological aspects contributes to the improvement of the fight against NHL in the DRC.
期刊介绍：
Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas:
Clinical Cancer Research
Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations
Cancer Biology:
Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery.
Cancer Prevention:
Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach.
Bioinformatics:
Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers.
Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.
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