西非冈比亚的年龄和性别特异性髋部骨折发病率和未来预测,以及非洲四个国家的比较。

IF 5.9 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Hannah Wilson, Kebba Marenah, Anya Burton, Momodou Jallow, Lucy Gates, Awa Touray, Samuel Hawley, Simon Graham, James Masters, Matthew Costa, Bintou Trawally, Kate A Ward, Celia L Gregson
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引用次数: 0

摘要

非洲人口的寿命正在增加,那里的贫困和营养不良很常见;因此,脆性骨折的发生率预计会增加。医疗保健系统必须适应这一老龄化人口;然而,目前西非地区的脆性骨折发生率尚未确定。本研究旨在确定冈比亚成人髋部骨折的年龄和性别发生率,并将其与其他南部非洲国家的发生率进行比较,并估计未来全国髋部骨折的预测。所有年龄≥40岁的成人髋部骨折病例,在研究区域的医院或传统的植骨师(TBS)就诊超过2年。使用2024年冈比亚人口普查估计每10万人年的年龄和性别特异性髋部骨折发生率。比较了冈比亚、津巴布韦、南非和博茨瓦纳的发病率估计值。在冈比亚,根据联合国的人口预测,估计了到2054年未来髋部骨折的数量。2年以上,226例髋部骨折患者,平均(标准差[SD])年龄71.2(12.5)岁,女性64.6%,住院184例(81.4%)或TBS 42例(18.6%)。多数表现为脆性骨折(205例[90.7%])。高冲击性创伤(如交通事故)在年轻男性中更为常见。延迟呈现是常见的(68例[30.1%])。冈比亚≥40岁成人的发病率,男性和女性分别为28.1 / 10万人年和51.7 / 10万人年,随年龄增长而增加。在年龄≥80岁的人群中,男性的发病率趋于稳定。髋部骨折的数量预计将从2024年的166例增加到2054年的621例。冈比亚、津巴布韦、博茨瓦纳和南非黑人的年龄特异性髋部骨折发生率大致相当。总之,冈比亚成年人脆性骨折很常见,表明与年龄相关的骨质疏松症。在未来的几十年里,髋部骨折病例几乎会翻四番;因此,必须扩大卫生服务能力,以应对这一不断增长的需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Age and sex specific incidence rates and future projections for hip fractures in the Gambia, West Africa, and comparison across four countries in Africa.

Longevity in African populations is increasing, where deprivation and malnutrition are common; hence fragility fracture incidence is expected to increase. Healthcare systems must adapt to provide for this aging population; however, currently fragility fracture incidence has yet to be determined in any West African setting. This study aimed to determine age- and sex-specific hip fracture incidence rates in adults in The Gambia, compare these with rates from other Southern African countries, and estimate future national hip fracture projections. All hip fracture cases in adults aged ≥40 yr, presenting to a hospital or traditional bone setter (TBS) in the study area over 2-yr, were identified. Age- and sex-specific hip fracture incidence per 100 000 person-years were estimated using the 2024 Gambian Population census. Incidence rate estimates were compared between The Gambia, Zimbabwe, South Africa, and Botswana. In The Gambia, future hip fracture numbers were estimated through to 2054 using United Nations population projections. Over 2-yr, 226 hip fracture patients, mean (standard deviation [SD]) age 71.2(12.5) years, 64.6% female, presented to hospital (184[81.4%]) or TBS (42[18.6%]). Most presented with a fragility fracture (205[90.7%]). High-impact trauma (eg, traffic accidents) was more common in younger men. Delays in presentation were common (68[30.1%]). Incidence rates for adults ≥40 yr in The Gambia were 28.1 and 51.7 per 100 000 person years for men and women, respectively, increasing with age. In those age ≥ 80 yr, incidence rates plateaued in men. The number of hip fractures is estimated to increase from 166 in 2024 to 621 by 2054. Age-specific hip fracture incidence rates were broadly comparable between The Gambia, Zimbabwe, Botswana, and Black South Africans. In summary, fragility fractures in Gambian adults were common, indicative of age-associated osteoporosis. Hip fracture cases will almost quadruple over coming decades; therefore, health service capacity must expand to manage this rising demand.

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来源期刊
Journal of Bone and Mineral Research
Journal of Bone and Mineral Research 医学-内分泌学与代谢
CiteScore
11.30
自引率
6.50%
发文量
257
审稿时长
2 months
期刊介绍: The Journal of Bone and Mineral Research (JBMR) publishes highly impactful original manuscripts, reviews, and special articles on basic, translational and clinical investigations relevant to the musculoskeletal system and mineral metabolism. Specifically, the journal is interested in original research on the biology and physiology of skeletal tissues, interdisciplinary research spanning the musculoskeletal and other systems, including but not limited to immunology, hematology, energy metabolism, cancer biology, and neurology, and systems biology topics using large scale “-omics” approaches. The journal welcomes clinical research on the pathophysiology, treatment and prevention of osteoporosis and fractures, as well as sarcopenia, disorders of bone and mineral metabolism, and rare or genetically determined bone diseases.
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