用商业吸附剂一步法从核医学用Sr-90中回收Y-90

IF 1.6 3区 化学 Q3 CHEMISTRY, ANALYTICAL
Andrey G. Kazakov, Daria V. Pavlova, Denis N. Dogadkin, Irina N. Gromyak, Vladimir P. Kolotov
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引用次数: 0

摘要

建立了提取色谱法从核医学用锶-90溶液中一步回收钇-90 (Y-90)的新方法。采用商业吸附剂TRU、DGA和LN对纯化后的Y-90进行定量回收。研究了锶、钇和杂质元素在模拟10 GBq放射性核素分离过程中的行为;结果表明,只有TRU适合运-90的大规模生产。使用该吸附剂Y-90的收率为80%,即使使用“化学纯”试剂,杂质元素水平也符合俄罗斯药典的要求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

One-step recovery of Y-90 from Sr-90 for nuclear medicine using commercial sorbents

One-step recovery of Y-90 from Sr-90 for nuclear medicine using commercial sorbents

One-step recovery of Y-90 from Sr-90 for nuclear medicine using commercial sorbents

New methods for one-step yttrium-90 (Y-90) recovery from strontium-90 (Sr-90) solutions for nuclear medicine using extraction chromatography were developed. Conditions for quantitative recovery of purified Y-90 for laboratory practice were found using commercial sorbents TRU, DGA and LN. The behavior of strontium, yttrium, and impurity elements in modeling the separation process of 10 GBq of studied radionuclides was studied; it was shown that only TRU is suitable for large-scale production of Y-90. The yield of Y-90 using this sorbent is 80%, and the impurity elements level meets the requirements of the Russian Pharmacopoeia even when using “chemically pure” reagents.

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来源期刊
CiteScore
2.80
自引率
18.80%
发文量
504
审稿时长
2.2 months
期刊介绍: An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.
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