鼻窦血管内乳头状内皮增生(Masson肿瘤):新病例报告并文献复习。

IF 2.2
Mousam Maiti, Mainak Dutta, Indranil Chakrabarti, Henna Ali, Sujaya Mazumder, Arundhati Mukherjee, Ajay Mallick
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引用次数: 0

摘要

目的:提供一例独特的鼻窦血管内乳头状内皮增生(IPEH; Masson肿瘤)的临床、放射学和组织病理学说明。方法:病例报告和文献回顾。结果:一名29岁男性患者表现为右侧鼻塞和偶尔带血的粘液脓毒两年。诊断性鼻内窥镜显示一肉质息肉状肿块占据右鼻腔,侵犯鼻咽部。那肿块又软又硬,一碰就流血。两个月前的钆增强磁共振成像显示右鼻腔内有一个巨大的非均匀肿块,部分累及上颌窦,并延伸至鼻咽部。这一发现在最近的对比增强计算机断层扫描中得到证实,该扫描显示由于肿块的扩张性而没有任何侵蚀,可见轻度对比剂摄取和骨重塑。感染后鼻息肉、血管肿瘤和肿瘤病变(包括内翻性乳头状瘤)被认为是鉴别。随后的穿刺活检显示提示IPEH的组织学图片。经鼻内窥镜完全切除肿物,发现肿物起源于右下鼻甲。最终的组织病理学证实了活检的结果。在活检和内镜下切除肿块的过程中都遇到了麻烦的出血。患者无症状,随访一年无复发。结论:鼻窦马松瘤是一种极为罕见的肿瘤;从PubMed/MEDLINE搜索中可以看出,在过去的40年里,只有14名患者被报道过。本报告补充了现有文献,总结了临床放射学和组织病理学的观点,强调了手术的挑战,并强调了将这种实体作为出血鼻窦肿块的鉴别诊断时具有低怀疑阈值的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sinonasal intravascular papillary endothelial hyperplasia (Masson's tumor): report of a new patient with review of literature.

Objective: To provide the clinico-radiologic and histopathologic illustration of a unique case of sinonasal intravascular papillary endothelial hyperplasia (IPEH; Masson's tumor).

Methodology: Case report and review of literature.

Results: A 29-year-old man presented with right-sided nasal obstruction and occasional blood-tinged mucopurulence for two years. Diagnostic naso-endoscopy revealed a fleshy polypoid mass occupying the right nasal cavity encroaching into the nasopharynx. The mass was tender and firm, and bled on touch. Gadolinium-enhanced magnetic resonance imaging done two months prior showed a large, heterogenous mass in the right nasal cavity, partly involving the maxillary sinus, and extending into the nasopharynx. The findings were corroborated in a recent contrast-enhanced computed tomography scan that revealed mild contrast uptake and bone remodeling due to expansile nature of the mass without any erosion. An infected antrochoanal polyp, vascular tumor, and neoplastic lesions (including inverted papilloma) were considered as differentials. A subsequent punch biopsy revealed histologic pictures suggestive of IPEH. The mass was excised completely through endonasal endoscopic approach, and it was found to originate from the right inferior turbinate. The final histopathology confirmed the biopsy findings. Troublesome bleeding was encountered both during the biopsy and endoscopic excision of the mass. The patient is symptom-free with no recurrence at one-year follow-up.

Conclusions: Sinonasal IPEH (Masson's tumor) is an extremely rare entity; only 14 patients have been reported in the last four decades as evident from the PubMed/MEDLINE search. The present report adds to the existing literature, summarizes the clinico-radiologic and histopathologic perspectives, highlights the surgical challenges, and underlines the importance of having a low threshold of suspicion for considering this entity as a differential in a bleeding sinonasal mass.

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