Pamela D'Netto, Emma Finch, Anna Rumbach, David A Copland
{"title":"吞咽功能、失语和重度语言障碍对血栓切除术后急性出院目的地的影响。","authors":"Pamela D'Netto, Emma Finch, Anna Rumbach, David A Copland","doi":"10.1044/2025_JSLHR-24-00866","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to describe the incidence of aphasia, high-level language impairment, and swallowing impairment in patients post-stroke treated with mechanical thrombectomy (MT) and to identify predictors of impairment and discharge destination.</p><p><strong>Method: </strong>This retrospective study examined impairments diagnosed by a speech-language pathologist in patients post-MT during their admission to the acute stroke unit. Multivariate logistic regression was used to determine the independent predictors of impairments and discharge to inpatient rehabilitation.</p><p><strong>Results: </strong>Language impairment was present in 66.4% (<i>n =</i> 249/375; <i>n =</i> 133 aphasia and <i>n =</i> 116 high-level impairment) and swallowing impairment in 59.1% (<i>n =</i> 238/403) of the patients. National Institute of Health Stroke Scale scores 24-hr post-MT were predictive of language (odds ratio [<i>OR</i>] <i>=</i> 1.09, 95% confidence interval [CI; 1.02, 1.16], <i>p</i> = .011) and swallowing (<i>OR =</i> 1.41, 95% CI [1.26, 1.58], <i>p</i> < .001) impairments. The occlusion site and medical complications post-MT were independently predictive of language and swallowing impairments, respectively. Diagnosed language impairment was a strong predictor of discharge for inpatient rehabilitation (<i>OR</i> = 4.77, 95% CI [1.60, 14.22], <i>p</i> = .005).</p><p><strong>Conclusions: </strong>Swallowing and language impairments, such as aphasia or high-level impairment, in isolation and in combination with other demographic and clinical variables, significantly influence the discharge trajectory of patients acutely post-MT. This information is vital for clinicians who need to prognosticate and plan rehabilitative care.</p><p><strong>Supplemental material: </strong>https://doi.org/10.23641/asha.30066892.</p>","PeriodicalId":520690,"journal":{"name":"Journal of speech, language, and hearing research : JSLHR","volume":" ","pages":"4607-4618"},"PeriodicalIF":2.2000,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influence of Swallowing Function, Aphasia and High-Level Language Impairment on Discharge Destination Acutely Post-Thrombectomy.\",\"authors\":\"Pamela D'Netto, Emma Finch, Anna Rumbach, David A Copland\",\"doi\":\"10.1044/2025_JSLHR-24-00866\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aimed to describe the incidence of aphasia, high-level language impairment, and swallowing impairment in patients post-stroke treated with mechanical thrombectomy (MT) and to identify predictors of impairment and discharge destination.</p><p><strong>Method: </strong>This retrospective study examined impairments diagnosed by a speech-language pathologist in patients post-MT during their admission to the acute stroke unit. Multivariate logistic regression was used to determine the independent predictors of impairments and discharge to inpatient rehabilitation.</p><p><strong>Results: </strong>Language impairment was present in 66.4% (<i>n =</i> 249/375; <i>n =</i> 133 aphasia and <i>n =</i> 116 high-level impairment) and swallowing impairment in 59.1% (<i>n =</i> 238/403) of the patients. National Institute of Health Stroke Scale scores 24-hr post-MT were predictive of language (odds ratio [<i>OR</i>] <i>=</i> 1.09, 95% confidence interval [CI; 1.02, 1.16], <i>p</i> = .011) and swallowing (<i>OR =</i> 1.41, 95% CI [1.26, 1.58], <i>p</i> < .001) impairments. The occlusion site and medical complications post-MT were independently predictive of language and swallowing impairments, respectively. Diagnosed language impairment was a strong predictor of discharge for inpatient rehabilitation (<i>OR</i> = 4.77, 95% CI [1.60, 14.22], <i>p</i> = .005).</p><p><strong>Conclusions: </strong>Swallowing and language impairments, such as aphasia or high-level impairment, in isolation and in combination with other demographic and clinical variables, significantly influence the discharge trajectory of patients acutely post-MT. This information is vital for clinicians who need to prognosticate and plan rehabilitative care.</p><p><strong>Supplemental material: </strong>https://doi.org/10.23641/asha.30066892.</p>\",\"PeriodicalId\":520690,\"journal\":{\"name\":\"Journal of speech, language, and hearing research : JSLHR\",\"volume\":\" \",\"pages\":\"4607-4618\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of speech, language, and hearing research : JSLHR\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1044/2025_JSLHR-24-00866\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of speech, language, and hearing research : JSLHR","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1044/2025_JSLHR-24-00866","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/18 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究旨在描述脑卒中后机械取栓(MT)治疗患者失语、高水平语言障碍和吞咽障碍的发生率,并确定损伤和出院目的地的预测因素。方法:本回顾性研究检查由语言病理学家诊断的脑卒中后患者在急性脑卒中住院期间的损伤。采用多因素logistic回归确定损伤和出院住院康复的独立预测因素。结果:66.4%的患者存在语言障碍(n = 249/375; n = 133例失语症,n = 116例高级障碍),59.1%的患者存在吞咽障碍(n = 238/403)。mt后24小时美国国立卫生研究院卒中量表评分可预测语言(优势比[OR] = 1.09, 95%可信区间[CI; 1.02, 1.16], p = 0.011)和吞咽(OR = 1.41, 95% CI [1.26, 1.58], p < 0.001)损伤。mt后的闭塞部位和医疗并发症分别独立预测语言和吞咽障碍。诊断出的语言障碍是住院康复出院的有力预测因子(OR = 4.77, 95% CI [1.60, 14.22], p = 0.005)。结论:吞咽和语言障碍,如失语或高级障碍,单独或联合其他人口统计学和临床变量,显著影响急性mt后患者的出院轨迹。这一信息对于需要预测和计划康复护理的临床医生至关重要。补充资料:https://doi.org/10.23641/asha.30066892。
Influence of Swallowing Function, Aphasia and High-Level Language Impairment on Discharge Destination Acutely Post-Thrombectomy.
Purpose: This study aimed to describe the incidence of aphasia, high-level language impairment, and swallowing impairment in patients post-stroke treated with mechanical thrombectomy (MT) and to identify predictors of impairment and discharge destination.
Method: This retrospective study examined impairments diagnosed by a speech-language pathologist in patients post-MT during their admission to the acute stroke unit. Multivariate logistic regression was used to determine the independent predictors of impairments and discharge to inpatient rehabilitation.
Results: Language impairment was present in 66.4% (n = 249/375; n = 133 aphasia and n = 116 high-level impairment) and swallowing impairment in 59.1% (n = 238/403) of the patients. National Institute of Health Stroke Scale scores 24-hr post-MT were predictive of language (odds ratio [OR] = 1.09, 95% confidence interval [CI; 1.02, 1.16], p = .011) and swallowing (OR = 1.41, 95% CI [1.26, 1.58], p < .001) impairments. The occlusion site and medical complications post-MT were independently predictive of language and swallowing impairments, respectively. Diagnosed language impairment was a strong predictor of discharge for inpatient rehabilitation (OR = 4.77, 95% CI [1.60, 14.22], p = .005).
Conclusions: Swallowing and language impairments, such as aphasia or high-level impairment, in isolation and in combination with other demographic and clinical variables, significantly influence the discharge trajectory of patients acutely post-MT. This information is vital for clinicians who need to prognosticate and plan rehabilitative care.