Yuan Gong, Yuanyuan Yang, Lintao Miao, Mingliang Zhong, Qidong Xia, Jie Chang, Shaogang Wang
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Flavonoid Intake and Kidney Stones: an Exposome-Based Cross-Sectional Study.
The present study aimed to evaluate the relationships between total, subgroup and individual dietary flavonoid intake and the risk of kidney stones. Data from the National Health and Nutrition Examination Survey and the Food and Nutrient Database for Dietary Studies were analyzed. A total of 9033 participants without kidney stones and 985 participants with kidney stones were included. A dose-response relationship curve suggested a J-shaped relationship (p for nonlinearity <0.001) between flavanone intake and kidney stone risk (nadir point: 32.23 mg/d, OR: 0.70, 95%CI: 0.58-0.84). Naringenin (a type of flavanones) was negatively associated with kidney stone risk. Hesperetin was associated with kidney stone risk in a J-shaped manner. These findings suggest that flavanone consumption may be beneficial for individuals with elevated kidney stone risk.
期刊介绍：
Devoted to advancements in nutritional sciences, The Journal of Nutritional Biochemistry presents experimental nutrition research as it relates to: biochemistry, molecular biology, toxicology, or physiology.
Rigorous reviews by an international editorial board of distinguished scientists ensure publication of the most current and key research being conducted in nutrition at the cellular, animal and human level. In addition to its monthly features of critical reviews and research articles, The Journal of Nutritional Biochemistry also periodically publishes emerging issues, experimental methods, and other types of articles.
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