银屑病关节炎的治疗进展：当前指南和新兴疗法。

IF 5.8 2区医学 Q1 IMMUNOLOGY

Current Opinion in Immunology Pub Date : 2025-09-16 DOI:10.1016/j.coi.2025.102658

Ashley M Feldkamp , Siba P Raychaudhuri

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引用次数: 0

摘要

银屑病关节炎（PsA）是一种影响周围和轴向关节、关节、皮肤和指甲的多方面自身免疫性疾病。PsA的管理依赖于及时诊断和早期开始有效的治疗，以尽量减少关节破坏。PsA的治疗方案正在迅速发展和出现。本综述将讨论PsA的筛查工具、早期诊断/结果测量和治疗指南，包括最新的EULAR/GRAPPA/ACR建议。科学技术的进步也在迅速改变医学领域，我们已经讨论了靶向治疗、智能手机监测和人工智能如何使PsA监测和治疗受益。最后，我们讨论了将PsA作为一种多系统疾病与多学科专家团队一起治疗的概念，并实施了“全面护理”计划。总的来说，这篇综述强调了PsA治疗框架的发展，提倡早期发现、全面评估和靶向治疗，以改善患者的预后和生活质量。

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Advances in treatment of psoriatic arthritis: current guidelines and emerging therapies

Psoriatic arthritis (PsA) is a multifaceted autoimmune condition that affects the peripheral and axial joints, entheses, skin, and nails. The management of PsA relies on prompt diagnosis and early initiation of effective treatment to minimize joint destruction. Treatment options for PsA are rapidly evolving and emerging. This review will discuss screening tools, early diagnosis/outcome measures, and treatment guidelines for PsA, including the most recent EULAR/GRAPPA/ACR recommendations. Advances in science and technology are also rapidly changing the landscape of medicine, and we have discussed how targeted therapies, smartphone monitoring, and artificial intelligence could benefit PsA monitoring and treatment. Finally, we discussed the concept of treating PsA as a multisystem disorder with a multidisciplinary team of specialists and implementation of a ‘Total Care’ program. Overall, this review highlights the evolving treatment frameworks in PsA, advocating for early detection, comprehensive assessment, and targeted therapy that can improve patient outcomes and quality of life.

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来源期刊

Current Opinion in Immunology 医学-免疫学

CiteScore

13.30

自引率

1.40%

发文量

审稿时长

67 days

期刊介绍： Current Opinion in Immunology aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed. In Current Opinion in Immunology we help the reader by providing in a systematic manner: 1. The views of experts on current advances in their field in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications. Current Opinion in Immunology will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students. Current Opinion in Immunology builds on Elsevier''s reputation for excellence in scientific publishing and long-standing commitment to communicating reproducible biomedical research targeted at improving human health. It is a companion to the new Gold Open Access journal Current Research in Immunology and is part of the Current Opinion and Research(CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy-of editorial excellence, high-impact, and global reach-to ensure they are a widely read resource that is integral to scientists'' workflow.