Jun Huang, Mintao Yan, Yanyu Li, Yuxin Chen, Kehong Wang
{"title":"双光束激光工艺参数对皮肤组织焊接力学性能及热损伤影响的研究。","authors":"Jun Huang, Mintao Yan, Yanyu Li, Yuxin Chen, Kehong Wang","doi":"10.1002/jbio.202500364","DOIUrl":null,"url":null,"abstract":"<p><p>Surgical incision closure and trauma repair are critical in surgery. Dual-beam laser tissue welding achieves full-layer skin tissue connection with minimal thermal damage via selective absorption of different laser wavelengths. This study investigates the impacts of laser scanning speed, spot spacing, and deflection angle on mechanical properties and thermal damage of skin tissues to optimize parameters. Through incision morphology observation, tensile strength tests, thermal denaturation analysis, and microtissue quantitative characterization, the optimal process parameters were obtained. Results show that tensile strength and thermal denaturation degree increase with scanning speed, exhibit a cyclic decreasing pattern with spot spacing, and significantly improve with deflection angle. When V = 200 mm/s, D = 0.5 mm, and θ = 60°, the incision achieves the highest connection strength, best thermal damage control, and overall performance. These findings provide technical references and data support for refined parameter models in vivo tests.</p>","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202500364"},"PeriodicalIF":2.3000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Research on the Effect of Dual-Beam Laser Process Parameters on the Mechanical Properties and Thermal Damage of Skin Tissue Welding.\",\"authors\":\"Jun Huang, Mintao Yan, Yanyu Li, Yuxin Chen, Kehong Wang\",\"doi\":\"10.1002/jbio.202500364\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Surgical incision closure and trauma repair are critical in surgery. Dual-beam laser tissue welding achieves full-layer skin tissue connection with minimal thermal damage via selective absorption of different laser wavelengths. This study investigates the impacts of laser scanning speed, spot spacing, and deflection angle on mechanical properties and thermal damage of skin tissues to optimize parameters. Through incision morphology observation, tensile strength tests, thermal denaturation analysis, and microtissue quantitative characterization, the optimal process parameters were obtained. Results show that tensile strength and thermal denaturation degree increase with scanning speed, exhibit a cyclic decreasing pattern with spot spacing, and significantly improve with deflection angle. When V = 200 mm/s, D = 0.5 mm, and θ = 60°, the incision achieves the highest connection strength, best thermal damage control, and overall performance. These findings provide technical references and data support for refined parameter models in vivo tests.</p>\",\"PeriodicalId\":94068,\"journal\":{\"name\":\"Journal of biophotonics\",\"volume\":\" \",\"pages\":\"e202500364\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biophotonics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/jbio.202500364\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/jbio.202500364","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
手术切口闭合和创伤修复是外科手术的关键。双光束激光组织焊接通过选择性吸收不同波长的激光,实现了皮肤组织的全层连接,热损伤最小。研究激光扫描速度、光斑间距和偏转角度对皮肤组织力学性能和热损伤的影响,并优化参数。通过切口形貌观察、拉伸强度试验、热变性分析、显微组织定量表征,获得最佳工艺参数。结果表明:拉伸强度和热变性程度随扫描速度的增加而增加,随光斑间距的增大而循环减小,随偏转角度的增大而显著提高;当V = 200 mm/s, D = 0.5 mm, θ = 60°时,切口连接强度最高,热损伤控制效果最好,综合性能最好。这些发现为精细化体内实验参数模型提供了技术参考和数据支持。
Research on the Effect of Dual-Beam Laser Process Parameters on the Mechanical Properties and Thermal Damage of Skin Tissue Welding.
Surgical incision closure and trauma repair are critical in surgery. Dual-beam laser tissue welding achieves full-layer skin tissue connection with minimal thermal damage via selective absorption of different laser wavelengths. This study investigates the impacts of laser scanning speed, spot spacing, and deflection angle on mechanical properties and thermal damage of skin tissues to optimize parameters. Through incision morphology observation, tensile strength tests, thermal denaturation analysis, and microtissue quantitative characterization, the optimal process parameters were obtained. Results show that tensile strength and thermal denaturation degree increase with scanning speed, exhibit a cyclic decreasing pattern with spot spacing, and significantly improve with deflection angle. When V = 200 mm/s, D = 0.5 mm, and θ = 60°, the incision achieves the highest connection strength, best thermal damage control, and overall performance. These findings provide technical references and data support for refined parameter models in vivo tests.