[影响孕32周以下非常早产的因素：一项多中心回顾性研究]。

Q3 Medicine

中国当代儿科杂志 Pub Date : 2025-07-15 DOI:10.7499/j.issn.1008-8830.2503096

Hong-Juan Wang, Rena Maimaiti, Yan-Ping Zhu, Yu-Jun Zhang, Hai-Li Li, Areziguli Abudula, Ying Li

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引用次数: 0

摘要

目的：探讨胎龄极早产的影响因素方法：回顾性收集2023年1月至2024年12月新疆省5家医院收治的早产妇女及其新生儿的临床资料。受试者按胎龄分为极早产儿（孕6周以上）组。分析与极早产相关的危险因素。结果：共纳入4105例早产孕妇，其中重度早产组793例（19.32%），中度/晚期早产组3312例（80.68%）。与极早产显著相关的因素有：妊娠期高血压疾病（OR=1.785, 95%CI: 1.492-2.135， POR=2.002, 95%CI: 1.672-2.397， POR=1.746, 95%CI: 1.326-2.300， POR=2.163, 95%CI: 1.694-2.763， POR=2.158, 95%CI: 1.599-2.912， POR=2.228, 95%CI: 1.646-3.014， POR=3.419, 95%CI: 2.882-4.055, p）在新疆维吾尔自治区，妊娠期高血压疾病、GWG过多或不足、绒毛膜羊膜炎、胎膜早破≥18小时、胎盘早剥、产前检查≤7次是重度早产的危险因素。加强高危妊娠管理对于减少极早产的发生率是必要的。

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[Factors influencing very preterm birth at less than 32 weeks of gestation: a multicenter retrospective study].

Objectives: To explore the influencing factors for very preterm birth at a gestational age of <32 weeks in the Xinjiang Uygur Autonomous Region.

Methods: Clinical data of women with preterm deliveries and their newborns admitted to five hospitals in Xinjiang from January 2023 to December 2024 were retrospectively collected. The subjects were divided by gestational age into very preterm (<32 weeks of gestation) and moderate/late preterm (32-36⁺⁶ weeks of gestation) groups. Risk factors associated with very preterm birth were analyzed.

Results: A total of 4 105 pregnant women with preterm deliveries were included, with 793 cases (19.32%) in the very preterm group and 3 312 cases (80.68%) in the moderate/late preterm group. The factors significantly associated with very preterm birth were as following: hypertensive disorders of pregnancy (OR=1.785, 95%CI: 1.492-2.135, P<0.05), excessive gestational weight gain (GWG, OR=2.002, 95%CI: 1.672-2.397, P<0.05), insufficient GWG (OR=1.746, 95%CI: 1.326-2.300, P<0.05), chorioamnionitis (OR=2.163, 95%CI: 1.694-2.763, P<0.05), premature rupture of membranes ≥18 hours (OR=2.158, 95%CI: 1.599-2.912, P<0.05), placental abruption (OR=2.228, 95%CI: 1.646-3.014, P<0.05), and ≤7 prenatal visits (OR=3.419, 95%CI: 2.882-4.055, P<0.05).

Conclusions: In the Xinjiang Uygur Autonomous Region, hypertensive disorders of pregnancy, excessive or insufficient GWG, chorioamnionitis, premature rupture of membranes ≥18 hours, placental abruption, and ≤7 prenatal visits are risk factors for very preterm birth. Strengthening high-risk pregnancy management is necessary for reducing the incidence of very preterm birth.

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来源期刊

中国当代儿科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.50

自引率

0.00%

发文量

5006

期刊介绍： The Chinese Journal of Contemporary Pediatrics (CJCP) is a peer-reviewed open access periodical in the field of pediatrics that is sponsored by the Central South University/Xiangya Hospital of Central South University and under the auspices of the Ministry of Education of China. It is cited as a source in the scientific and technological papers of Chinese journals, the Chinese Science Citation Database (CSCD), and is one of the core Chinese periodicals in the Peking University Library. CJCP has been indexed by MEDLINE/PubMed/PMC of the American National Library, American Chemical Abstracts (CA), Holland Medical Abstracts (EM), Western Pacific Region Index Medicus (WPRIM), Scopus and EBSCO. It is a monthly periodical published on the 15th of every month, and is distributed both at home and overseas. The Chinese series publication number is CN 43-1301/R；ISSN 1008-8830. The tenet of CJCP is to “reflect the latest advances and be open to the world”. The periodical reports the most recent advances in the contemporary pediatric field. The majority of the readership is pediatric doctors and researchers.