三皮质螺钉脊柱固定:对高危椎体骨折的技术、生物力学优势和临床结果进行综述和介绍。

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Hanyu Qiu, Daniel O'Connor, Kishore Balasubramanian, Graham G Mulvaney, Beste Gulsuna, Abigail A York, Chao Li DO
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引用次数: 0

摘要

背景/目的:三皮质椎弓根螺钉(TCPS)固定已成为一种生物力学上优于传统单皮质/双皮质方法的方法,用于高危人群的脊柱稳定,特别是老年骨质疏松或弥漫性特发性骨骼增生(DISH)相关椎体骨折患者。本综述评估了TCPS固定的生物力学优势、临床结果和应对这些挑战的手术考虑。方法:使用PRISMA范围审查清单进行范围审查。PubMed的搜索截止到2025年3月1日。纳入标准为报道TCPS脊柱固定治疗参数和随访结果的研究。分析数据以综合临床结果,重点关注硬件故障率。结果:5项研究符合最终纳入标准,包括3个病例系列和2个队列。这5项研究包括85例患者。纳入的患者加权平均年龄为78.97岁,性别分布为男性占54.8% (n = 40),女性占45.2% (n = 33)。62.4% (n = 53)患者DISH阳性。受累椎主要位于胸腰椎区(64.1%),其次是胸椎区(21.8%)和腰椎区(14.1%)。76.5% (n = 65)的患者采用TCPS固定治疗,23.5% (n = 20)的患者采用常规治疗。共置入636枚螺钉,其中46.2% (n = 294)为三皮层螺钉,53.8% (n = 342)为常规椎弓根螺钉。三皮质螺钉中有1.36% (n = 4)松动,而常规螺钉中有20.5% (n = 70)松动。3例采用TCPS内固定,6例采用常规椎弓根螺钉内固定。结论:TCPS内固定通过三皮质负荷分布增强了高危骨折的脊柱稳定,减少了螺钉松动和侵入性。虽然需要精确的轨迹规划来避免穿孔风险,但它可以缩短手术时间,减少失血,提高生物力学稳定性,特别是对骨质疏松症/DISH患者。需要进一步的前瞻性研究来优化患者选择和完善导航辅助技术以获得更广泛的适用性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Tricortical screw spinal fixation: a scoping review and introduction of technique, biomechanical advantages, and clinical outcomes in high-risk vertebral fractures.

Tricortical screw spinal fixation: a scoping review and introduction of technique, biomechanical advantages, and clinical outcomes in high-risk vertebral fractures.

Tricortical screw spinal fixation: a scoping review and introduction of technique, biomechanical advantages, and clinical outcomes in high-risk vertebral fractures.

Tricortical screw spinal fixation: a scoping review and introduction of technique, biomechanical advantages, and clinical outcomes in high-risk vertebral fractures.

Background/objective: Tricortical pedicle screw (TCPS) fixation has emerged as a biomechanically superior alternative to conventional unicortical/bicortical methods for spinal stabilization in high-risk populations, particularly elderly patients with osteoporotic or diffuse idiopathic skeletal hyperostosis (DISH)-related vertebral fractures. This review evaluates TCPS fixation's biomechanical advantages, clinical outcomes, and surgical considerations to address these challenges.

Methods: A scoping review was conducted using the PRISMA scoping review checklist. PubMed was searched through March 1, 2025. Inclusion criteria were studies reporting treatment parameters and follow-up results of TCPS spinal fixation. Data was analyzed to synthesize clinical outcomes, with a focus on hardware failure rates.

Results: 5 studies satisfied the final inclusion criteria, consisting of 3 case series and 2 cohorts. These 5 studies included 85 patient cases. The included patients had a weighted mean age of 78.97 years, with a sex distribution consisting of 54.8% (n = 40) males and 45.2% (n = 33) females. 62.4% (n = 53) patients were positive for DISH. Affected vertebrae were mostly located in the thoracolumbar region (64.1%), followed by the thoracic (21.8%) and lumbar regions (14.1%). 76.5% (n = 65) of patients were treated with TCPS fixation, and 23.5% (n = 20) were treated conventionally. A total of 636 screws were inserted, consisting of 46.2% (n = 294) tricortical and 53.8% (n = 342) conventional pedicle screws. Of the tricortical screws, 1.36% (n = 4) loosened, while 20.5% (n = 70) of conventional screws loosened. 3 patients treated with TCPS fixation experienced implant failure, while 6 patients treated with conventional pedicle screw fixation experienced implant failure.

Conclusion: TCPS fixation enhances spinal stabilization in high-risk fractures through tri-cortical load distribution, minimizing screw loosening and invasiveness. While requiring precise trajectory planning to avoid perforation risks, it offers shorter operative times, reduced blood loss, and improved biomechanical stability, particularly in osteoporotic/DISH patients. Further prospective studies are needed to optimize patient selection and refine navigation-assisted techniques for broader applicability.

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来源期刊
Neurosurgical Review
Neurosurgical Review 医学-临床神经学
CiteScore
5.60
自引率
7.10%
发文量
191
审稿时长
6-12 weeks
期刊介绍: The goal of Neurosurgical Review is to provide a forum for comprehensive reviews on current issues in neurosurgery. Each issue contains up to three reviews, reflecting all important aspects of one topic (a disease or a surgical approach). Comments by a panel of experts within the same issue complete the topic. By providing comprehensive coverage of one topic per issue, Neurosurgical Review combines the topicality of professional journals with the indepth treatment of a monograph. Original papers of high quality are also welcome.
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