{"title":"维生素控制肥胖/肥胖的治疗作用和机制——近期研究综述。","authors":"Md Hasinur Rahman, Md Ibrahim H Mondal","doi":"10.1038/s41366-025-01908-0","DOIUrl":null,"url":null,"abstract":"<p><p>Obesity/adiposity, an often-intractable disease with serious physical, economic, and societal consequences, is a major problem for health practitioners. Despite extensive research, obesity remains a kind of pandemic. There is significant evidence that individuals with obesity react to both fat-soluble and water-soluble vitamin levels in their serum. Vitamins correlate negatively with body weight, body mass index, and body composition. Certain vitamins may possess anti-adipogenic, anti-inflammatory, and antioxidant properties. Yet still, there is no consensus among researchers about the general impact of vitamins on obesity. A clearer understanding of the effects of vitamins on obesity will make dietary interventions more effective in preventing and treating obesity and its complications. This article analyses the current data about the impact of vitamins on controlling obesity, including their role, action mechanisms and obesity-related metabolic statuses. Such an analysis could enhance our understanding of the effects of vitamins on obesity. So, this article could assist future researchers who are working toward better protocols for treating obesity.</p>","PeriodicalId":14183,"journal":{"name":"International Journal of Obesity","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic role and mechanisms of vitamins for controlling obesity/adiposity-a brief overview of recent studies.\",\"authors\":\"Md Hasinur Rahman, Md Ibrahim H Mondal\",\"doi\":\"10.1038/s41366-025-01908-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Obesity/adiposity, an often-intractable disease with serious physical, economic, and societal consequences, is a major problem for health practitioners. Despite extensive research, obesity remains a kind of pandemic. There is significant evidence that individuals with obesity react to both fat-soluble and water-soluble vitamin levels in their serum. Vitamins correlate negatively with body weight, body mass index, and body composition. Certain vitamins may possess anti-adipogenic, anti-inflammatory, and antioxidant properties. Yet still, there is no consensus among researchers about the general impact of vitamins on obesity. A clearer understanding of the effects of vitamins on obesity will make dietary interventions more effective in preventing and treating obesity and its complications. This article analyses the current data about the impact of vitamins on controlling obesity, including their role, action mechanisms and obesity-related metabolic statuses. Such an analysis could enhance our understanding of the effects of vitamins on obesity. So, this article could assist future researchers who are working toward better protocols for treating obesity.</p>\",\"PeriodicalId\":14183,\"journal\":{\"name\":\"International Journal of Obesity\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-09-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Obesity\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1038/s41366-025-01908-0\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Obesity","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41366-025-01908-0","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Therapeutic role and mechanisms of vitamins for controlling obesity/adiposity-a brief overview of recent studies.
Obesity/adiposity, an often-intractable disease with serious physical, economic, and societal consequences, is a major problem for health practitioners. Despite extensive research, obesity remains a kind of pandemic. There is significant evidence that individuals with obesity react to both fat-soluble and water-soluble vitamin levels in their serum. Vitamins correlate negatively with body weight, body mass index, and body composition. Certain vitamins may possess anti-adipogenic, anti-inflammatory, and antioxidant properties. Yet still, there is no consensus among researchers about the general impact of vitamins on obesity. A clearer understanding of the effects of vitamins on obesity will make dietary interventions more effective in preventing and treating obesity and its complications. This article analyses the current data about the impact of vitamins on controlling obesity, including their role, action mechanisms and obesity-related metabolic statuses. Such an analysis could enhance our understanding of the effects of vitamins on obesity. So, this article could assist future researchers who are working toward better protocols for treating obesity.
期刊介绍:
The International Journal of Obesity is a multi-disciplinary forum for research describing basic, clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders.
We publish a range of content types including original research articles, technical reports, reviews, correspondence and brief communications that elaborate on significant advances in the field and cover topical issues.