Konstantina Spetsotaki, Matthias Menne, Ajay Moza, Shahram Lotfi, Ali Aljaloud
{"title":"直观与经腹主动脉生物假体的生物力学比较:苹果和橘子还是摇摆和迂回?","authors":"Konstantina Spetsotaki, Matthias Menne, Ajay Moza, Shahram Lotfi, Ali Aljaloud","doi":"10.1186/s13019-025-03567-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Rapid deployment (RD) and sutureless (SU) aortic valve replacement (AVR) are established strategies with proven benefits and ongoing evolution. In this study, we compare the clinical results and technical attributes of RDAVR and SUAVR with the two most commonly applied bioprostheses, the Edwards Intuity Valve System and the Perceval sutureless.</p><p><strong>Methods: </strong>N=19 patients with Intuity AVR were matched to N=19 with Perceval AVR from 2014 to 2020 at University Hospital Aachen, RWTH. Preoperative and postoperative data were compared. OSIRIX DICOM software was used for 4D stent analysis 30 days post-surgery. Additional in vitro evaluation of the Perceval and Intuity Valve Systems' radial forces was conducted.</p><p><strong>Results: </strong>In-hospital and 30-day mortality was 2/19(10.5%) in both groups. Patients in the Perceval group had higher MPG score value than those in the Intuity group (13.96 vs. 10.70; p=0.041). Patients in the Perceval group had significantly higher mean values of postoperative PPG than those in the Intuity group (26.34 vs. 19.52, p-value = 0.018). The Intuity group showed higher roundness in CT analyses after AVR and higher radial forces than the Intuity group during the in-vitro testing.</p><p><strong>Conclusion: </strong>We report interesting differences regarding the biomechanical behavior of the stents' ovality and radial forces of the two prostheses. However, the early postoperative clinical outcome remains comparable. Further studies with larger cohorts and long-term mechanical analysis are needed for deeper insights into this complex entity.</p>","PeriodicalId":15201,"journal":{"name":"Journal of Cardiothoracic Surgery","volume":"20 1","pages":"351"},"PeriodicalIF":1.5000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442290/pdf/","citationCount":"0","resultStr":"{\"title\":\"Biomechanical comparison of intuity vs. perceval aortic bioprosthesis: apples & oranges or swings & roundabouts?\",\"authors\":\"Konstantina Spetsotaki, Matthias Menne, Ajay Moza, Shahram Lotfi, Ali Aljaloud\",\"doi\":\"10.1186/s13019-025-03567-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Rapid deployment (RD) and sutureless (SU) aortic valve replacement (AVR) are established strategies with proven benefits and ongoing evolution. In this study, we compare the clinical results and technical attributes of RDAVR and SUAVR with the two most commonly applied bioprostheses, the Edwards Intuity Valve System and the Perceval sutureless.</p><p><strong>Methods: </strong>N=19 patients with Intuity AVR were matched to N=19 with Perceval AVR from 2014 to 2020 at University Hospital Aachen, RWTH. Preoperative and postoperative data were compared. OSIRIX DICOM software was used for 4D stent analysis 30 days post-surgery. Additional in vitro evaluation of the Perceval and Intuity Valve Systems' radial forces was conducted.</p><p><strong>Results: </strong>In-hospital and 30-day mortality was 2/19(10.5%) in both groups. Patients in the Perceval group had higher MPG score value than those in the Intuity group (13.96 vs. 10.70; p=0.041). Patients in the Perceval group had significantly higher mean values of postoperative PPG than those in the Intuity group (26.34 vs. 19.52, p-value = 0.018). The Intuity group showed higher roundness in CT analyses after AVR and higher radial forces than the Intuity group during the in-vitro testing.</p><p><strong>Conclusion: </strong>We report interesting differences regarding the biomechanical behavior of the stents' ovality and radial forces of the two prostheses. However, the early postoperative clinical outcome remains comparable. Further studies with larger cohorts and long-term mechanical analysis are needed for deeper insights into this complex entity.</p>\",\"PeriodicalId\":15201,\"journal\":{\"name\":\"Journal of Cardiothoracic Surgery\",\"volume\":\"20 1\",\"pages\":\"351\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-09-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442290/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cardiothoracic Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s13019-025-03567-8\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cardiothoracic Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13019-025-03567-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Biomechanical comparison of intuity vs. perceval aortic bioprosthesis: apples & oranges or swings & roundabouts?
Introduction: Rapid deployment (RD) and sutureless (SU) aortic valve replacement (AVR) are established strategies with proven benefits and ongoing evolution. In this study, we compare the clinical results and technical attributes of RDAVR and SUAVR with the two most commonly applied bioprostheses, the Edwards Intuity Valve System and the Perceval sutureless.
Methods: N=19 patients with Intuity AVR were matched to N=19 with Perceval AVR from 2014 to 2020 at University Hospital Aachen, RWTH. Preoperative and postoperative data were compared. OSIRIX DICOM software was used for 4D stent analysis 30 days post-surgery. Additional in vitro evaluation of the Perceval and Intuity Valve Systems' radial forces was conducted.
Results: In-hospital and 30-day mortality was 2/19(10.5%) in both groups. Patients in the Perceval group had higher MPG score value than those in the Intuity group (13.96 vs. 10.70; p=0.041). Patients in the Perceval group had significantly higher mean values of postoperative PPG than those in the Intuity group (26.34 vs. 19.52, p-value = 0.018). The Intuity group showed higher roundness in CT analyses after AVR and higher radial forces than the Intuity group during the in-vitro testing.
Conclusion: We report interesting differences regarding the biomechanical behavior of the stents' ovality and radial forces of the two prostheses. However, the early postoperative clinical outcome remains comparable. Further studies with larger cohorts and long-term mechanical analysis are needed for deeper insights into this complex entity.
期刊介绍:
Journal of Cardiothoracic Surgery is an open access journal that encompasses all aspects of research in the field of Cardiology, and Cardiothoracic and Vascular Surgery. The journal publishes original scientific research documenting clinical and experimental advances in cardiac, vascular and thoracic surgery, and related fields.
Topics of interest include surgical techniques, survival rates, surgical complications and their outcomes; along with basic sciences, pediatric conditions, transplantations and clinical trials.
Journal of Cardiothoracic Surgery is of interest to cardiothoracic and vascular surgeons, cardiothoracic anaesthesiologists, cardiologists, chest physicians, and allied health professionals.