呼吸衰竭早产儿肺超声评分和左心室偏心率指数的初步研究。

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-09-17 DOI:10.1038/s41372-025-02429-4

Jacob Kelner, Naveed Hussain, Henry Chicaiza, Shalin Parekh

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引用次数: 0

摘要

目的：探讨呼吸衰竭早产儿肺超声评分（LUS）与收缩期末和舒张期末左心室偏心指数（LVEI-s）的关系。研究设计：这项前瞻性先导研究包括对20名出生时需要无创通气的伴有新生儿短暂性呼吸急促（TTN）和呼吸窘迫综合征（RDS）的早产儿进行38次超声检查。每天取LUS、LVEI-s和LVEI-d，持续72h。采用线性回归分析确定相关性。结果：LUS与LVEI-s呈正相关（r = 0.47, p =）。结论：随着LUS的增加，RDS患儿LVEI-s和LVEI-d均出现可测量的变化。这种关联可以提高诊断分层的准确性和优化新生儿肺部疾病的液体管理。

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Lung ultrasound score and left ventricular eccentricity index in preterm infants with respiratory failure - a pilot study.

Objective: To investigate the association between lung ultrasound score (LUS) and left ventricular eccentricity index at end-systole (LVEI-s) and end-diastole (LVEI-d) in preterm infants with respiratory failure.

Study design: This prospective pilot study included 38 ultrasounds on 20 premature infants with Transient Tachypnea of the Newborn (TTN) and Respiratory Distress Syndrome (RDS) requiring non-invasive ventilation at birth. LUS, LVEI-s, and LVEI-d were obtained daily for 72 h. Linear regression analysis was performed to determine correlation.

Results: LUS positively correlated with LVEI-s (r = 0.47, p = <0.01) and LVEI-d (r = 0.63, p = <0.01) during the 72-hour study period in the RDS group, but not the TTN group. Correlation increased over the first 24 h (LVEI-s: r = 0.69, p = <0.01; LVEI-d: r = 0.68, p = <0.01) in the RDS group.

Conclusion: As LUS increases, both LVEI-s and LVEI-d demonstrate measurable changes in infants with RDS. This association may enhance precision in diagnostic stratification and optimizing fluid management in neonatal lung disease.

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.