一种基于阻力反馈理论的脉络膜上注射器用于治疗黄斑水肿:一项短期试点研究。

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY
Dandan Zhang, Qiuyi Zhu, Rong Huang, Ai Zhuang, Dongqing Zhu
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引用次数: 0

摘要

目的探讨一种基于阻力反馈理论的脉络膜上腔注射新技术,采用精巧、手工、精密的脉络膜上腔注射器治疗复发性黄斑水肿。方法基于电阻反馈理论,设计了脉络膜上注射器,并用现成的工业材料制作。9例继发于糖尿病视网膜病变或视网膜静脉阻塞的复发性黄斑水肿患者,因无法承受反复抗血管内皮生长因子治疗,采用该注射器在脉络膜上注射曲安奈德。观察注射前后SCS、黄斑水肿和视力的变化。结果所有患者注射后,前段光学相干断层扫描均显示SCS即刻扩张。注射后1个月,光谱域光学相干断层扫描显示黄斑水肿减轻,平均中心亚场厚度从574.56±151.53 μm减少到338.78±61.26 μm,最佳矫正视力从0.87±0.29 logMAR改善到0.55±0.24 logMAR。无眼压升高、白内障、视网膜损伤、玻璃体腔内注液等并发症。结论该注射器可提供一种经济、安全、精确的SCS注射方法,具有广泛的临床应用潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An ingenious suprachoroidal injector based on the resistance feedback theory for treatment of macular edema: A short-term pilot study.

PurposeTo explore a new suprachoroidal space (SCS) injection technique using an ingenious, handmade, and precise suprachoroidal injector based on the resistance feedback theory to treat recurrent macular edema.MethodsWe designed a suprachoroidal injector on the basis of the resistance feedback theory and fabricated it with readily available commercial materials. Nine patients with recurrent macular edema secondary to diabetic retinopathy or retinal vein occlusion who could not afford repeated anti-vascular endothelial growth factor treatment received suprachoroidal injection of triamcinolone acetonide using this injector. Changes in SCS, macular edema and visual acuity before and after injection were evaluated.ResultsIn all patients, anterior-segment optical coherence tomography revealed SCS expansion immediately after injection. At 1 month after injection, spectral-domain optical coherence tomography revealed a reduction in macular edema with average central subfield thickness decreasing from 574.56 ± 151.53 μm to 338.78 ± 61.26 μm, and best-corrected visual acuity improved from 0.87 ± 0.29 logMAR to 0.55 ± 0.24 logMAR. Complications such as increased intraocular pressure, cataract, retinal damage and fluid injection into the vitreous cavity were not observed.ConclusionsThis new injector is expected to provide an economical, safe, and precise SCS injection and may have potential for widely clinical application.

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来源期刊
CiteScore
3.60
自引率
0.00%
发文量
372
审稿时长
3-8 weeks
期刊介绍: The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.
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