Miguel Carabaño, Eunji Jang, Swapna Charla, Gerard Nau, Sara Geffert, Ece D Gamsiz Uzun, Tao Hong
{"title":"广谱产β -内酰胺酶大肠杆菌序列58型菌株(ST58)具有固体皮下肿块和高黏液样表型:1例报告。","authors":"Miguel Carabaño, Eunji Jang, Swapna Charla, Gerard Nau, Sara Geffert, Ece D Gamsiz Uzun, Tao Hong","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p><i>Escherichia coli</i> (<i>E. coli</i>) is a versatile bacterium, presenting a wide variety of virulence factors contributing to intestinal and extraintestinal disease. This paper presents a unique case of <i>Escherichia coli</i> strain exhibiting an extended-spectrum beta-lactamase (ESBL) as determined by minimum inhibitory concentration (MIC), identified as sequence type 58 (ST58). The strain, isolated from a clinical specimen, displayed unusual characteristics, forming a solid subcutaneous mass and presenting a hypermucoid phenotype. Comprehensive analysis, including whole-genome sequencing (WGS) and conventional serotyping, was conducted to understand the genetic and phenotypic features of this atypical <i>E. coli</i> strain.</p>","PeriodicalId":8228,"journal":{"name":"Annals of clinical and laboratory science","volume":"55 4","pages":"590-595"},"PeriodicalIF":1.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Presentation of Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia Coli</i> Sequence Type 58 Strain (ST58) with Solid Subcutaneous Mass and Hypermucoid Phenotype: A Case Report.\",\"authors\":\"Miguel Carabaño, Eunji Jang, Swapna Charla, Gerard Nau, Sara Geffert, Ece D Gamsiz Uzun, Tao Hong\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>Escherichia coli</i> (<i>E. coli</i>) is a versatile bacterium, presenting a wide variety of virulence factors contributing to intestinal and extraintestinal disease. This paper presents a unique case of <i>Escherichia coli</i> strain exhibiting an extended-spectrum beta-lactamase (ESBL) as determined by minimum inhibitory concentration (MIC), identified as sequence type 58 (ST58). The strain, isolated from a clinical specimen, displayed unusual characteristics, forming a solid subcutaneous mass and presenting a hypermucoid phenotype. Comprehensive analysis, including whole-genome sequencing (WGS) and conventional serotyping, was conducted to understand the genetic and phenotypic features of this atypical <i>E. coli</i> strain.</p>\",\"PeriodicalId\":8228,\"journal\":{\"name\":\"Annals of clinical and laboratory science\",\"volume\":\"55 4\",\"pages\":\"590-595\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of clinical and laboratory science\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of clinical and laboratory science","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
Presentation of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Sequence Type 58 Strain (ST58) with Solid Subcutaneous Mass and Hypermucoid Phenotype: A Case Report.
Escherichia coli (E. coli) is a versatile bacterium, presenting a wide variety of virulence factors contributing to intestinal and extraintestinal disease. This paper presents a unique case of Escherichia coli strain exhibiting an extended-spectrum beta-lactamase (ESBL) as determined by minimum inhibitory concentration (MIC), identified as sequence type 58 (ST58). The strain, isolated from a clinical specimen, displayed unusual characteristics, forming a solid subcutaneous mass and presenting a hypermucoid phenotype. Comprehensive analysis, including whole-genome sequencing (WGS) and conventional serotyping, was conducted to understand the genetic and phenotypic features of this atypical E. coli strain.
期刊介绍:
The Annals of Clinical & Laboratory Science
welcomes manuscripts that report research in clinical
science, including pathology, clinical chemistry,
biotechnology, molecular biology, cytogenetics,
microbiology, immunology, hematology, transfusion
medicine, organ and tissue transplantation, therapeutics, toxicology, and clinical informatics.