丙炔醇与含硫试剂直接转化的研究进展。

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC
Jiayi Chao, Rumeng Yang, Jiarui Huang, Xi Chen, Xian-Rong Song and Qiang Xiao
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引用次数: 0

摘要

含硫化合物是一类重要的有机化合物,广泛应用于医药、农业、材料科学、天然产物和有机合成等领域。因此,开发含硫化合物的合成策略已成为合成化学领域的一个重要研究课题。此外,具有独特双官能团的丙炔醇已成为有机合成中有前途的多功能合成物。在过去的几十年里(直到现在),通过用各种含硫试剂直接转化丙炔醇来构造这些化合物已经做出了相当大的努力。本文系统地介绍了丙炔醇与含硫试剂直接转化制备含硫化合物的研究进展。基于这些转化的不同反应机理,本文分为四个部分进行综述:(1)碱促进丙炔醇与含硫试剂的直接转化;(2)酸促/催化丙炔醇与含硫试剂的直接转化;(3)金属催化含硫试剂直接转化丙炔醇;(4)丙炔醇与含硫试剂的自由基转化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Advances in the direct transformations of propargylic alcohols and sulphur-containing reagents

Advances in the direct transformations of propargylic alcohols and sulphur-containing reagents

Sulphur-containing compounds are regarded as an important class of organic compounds that are widely applied in pharmaceuticals, agriculture, materials sciences, natural products, and organic synthesis. Consequently, the development of synthetic strategies for sulphur-containing compounds has become a prominent research topic in synthetic chemistry. Additionally, propargylic alcohols with unique bifunctional groups have emerged as promising and versatile synthons in organic synthesis. Over the past few decades (until the present), considerable efforts have been made to construct these compounds through the direct transformation of propargylic alcohols with various sulphur-containing reagents. This review systematically highlights these advances in the direct transformation of propargylic alcohols with sulphur-containing reagents for the construction of sulphur-containing compounds. Based on the different reaction mechanisms underlying these transformations, this review is divided into four sections: (1) base-promoted direct transformation of propargylic alcohols with sulphur-containing reagents; (2) acid-promoted/catalyzed direct transformation of propargylic alcohols with sulphur-containing reagents; (3) metal-catalyzed direct transformation of propargylic alcohols with sulphur-containing reagents; and (4) radical transformation of propargylic alcohols with sulphur-containing reagents.

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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
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