Lauren Michiels, Mahrukh Shameem, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Simon A Johnston, Nicolas Beziere, Greetje Vande Velde
{"title":"聚焦真菌感染：加速非侵入性成像从临床前洞察到临床突破。","authors":"Lauren Michiels, Mahrukh Shameem, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Simon A Johnston, Nicolas Beziere, Greetje Vande Velde","doi":"10.1038/s44303-025-00105-y","DOIUrl":null,"url":null,"abstract":"<p><p>Invasive fungal diseases (IFDs) present a growing clinical challenge, underscoring the urgent need for improved diagnostics, therapeutics and mechanistic understanding. This review highlights the key role of innovative imaging techniques across all scales - ranging from whole-body-level diagnostics and therapy monitoring to host-pathogen interactions at cellular resolution in both clinical and preclinical settings. These imaging modalities facilitate translation of preclinical innovations into clinical applications, accelerating research and advancing IFD management.</p>","PeriodicalId":501709,"journal":{"name":"npj Imaging","volume":"3 1","pages":"42"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12441154/pdf/","citationCount":"0","resultStr":"{\"title\":\"Fungal infections in focus: accelerating non-invasive imaging from preclinical insights to clinical breakthroughs.\",\"authors\":\"Lauren Michiels, Mahrukh Shameem, Eliane Vanhoffelen, Agustin Reséndiz-Sharpe, Simon A Johnston, Nicolas Beziere, Greetje Vande Velde\",\"doi\":\"10.1038/s44303-025-00105-y\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Invasive fungal diseases (IFDs) present a growing clinical challenge, underscoring the urgent need for improved diagnostics, therapeutics and mechanistic understanding. This review highlights the key role of innovative imaging techniques across all scales - ranging from whole-body-level diagnostics and therapy monitoring to host-pathogen interactions at cellular resolution in both clinical and preclinical settings. These imaging modalities facilitate translation of preclinical innovations into clinical applications, accelerating research and advancing IFD management.</p>\",\"PeriodicalId\":501709,\"journal\":{\"name\":\"npj Imaging\",\"volume\":\"3 1\",\"pages\":\"42\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12441154/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"npj Imaging\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1038/s44303-025-00105-y\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"npj Imaging","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s44303-025-00105-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fungal infections in focus: accelerating non-invasive imaging from preclinical insights to clinical breakthroughs.
Invasive fungal diseases (IFDs) present a growing clinical challenge, underscoring the urgent need for improved diagnostics, therapeutics and mechanistic understanding. This review highlights the key role of innovative imaging techniques across all scales - ranging from whole-body-level diagnostics and therapy monitoring to host-pathogen interactions at cellular resolution in both clinical and preclinical settings. These imaging modalities facilitate translation of preclinical innovations into clinical applications, accelerating research and advancing IFD management.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
