帕金森病患者步态参数与临床量表的相关性

Q3 Medicine
Dementia e Neuropsychologia Pub Date : 2025-09-05 eCollection Date: 2025-01-01 DOI:10.1590/1980-5764-DN-2024-0205
Adriana Tanigawa Bitiati, Marina Ortega Golin, Daniel Boari Coelho
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引用次数: 0

摘要

独立行走的能力对于帕金森病患者(PD)的生活质量至关重要,而行动能力、平衡能力和认知能力等方面对行走都很重要。然而,这些因素之间的联系尚未完全确定。目的:验证PD患者认知、运动临床量表和步态间隔的相关性。方法:对22例临床诊断为特发性PD的患者进行评估,采用平衡和认知测试对疾病的严重程度进行分类,并在实验室进行步态分析。结果:统一帕金森病评定量表运动部分(UPDRS-III)与停药状态下步宽直接相关(p=0.029);在用药ON (p=0.001)和OFF (p=0.005)状态下,平衡评估系统Mini-Test (mini - best)与步宽成反比;在给药状态下,Stroop-III与步幅时间(p=0.039)、站姿(p=0.003)和双站姿(p=0.011)相成正比,与步幅(p=0.033)和摇摆相(p=0.003)成反比;在ON状态下,造径测试A部分(TMTB-A)与步长(p=0.035)、步幅(p=0.037)、节奏(p=0.036)和速度(p=0.003)成反比。结论:认知功能障碍与PD患者的步态不稳定直接相关,加强运动和认知康复综合干预的重要性。这些策略可以提高PD患者的步态安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation between gait parameters and clinical scales in individuals with Parkinson's disease.

The ability to walk independently is essential for the quality of life of individuals with Parkinson's disease (PD), and aspects such as mobility, balance, and cognition are important for walking. However, the association between these factors has not yet been fully established.

Objective: To verify the correlations between cognitive and motor clinical scales, and gait intervals in individuals with PD.

Methods: Twenty-two individuals with a clinical diagnosis of idiopathic PD were evaluated using balance and cognitive tests to classify the severity of the disease and gait analysis in the laboratory.

Results: The Unified Parkinson's Disease Rating Scale, motor part (UPDRS-III) was directly related to step width in the OFF state of medication (p=0.029); the Mini-Test of Balance Assessment System (Mini-BESTest) was inversely proportional to step width in medication ON (p=0.001) and OFF (p=0.005) states; Stroop-III was directly proportional to the stride time (p=0.039) and the stance (p=0.003) and double stance (p=0.011) phases and inversely proportional to the cadence (p=0.033) and swing phase (p=0.003), both in the ON state of medication; the Trail Making Test Part A (TMTB-A) was inversely proportional to step size (p=0.035), stride size (p=0.037), cadence (p=0.036) and speed (p=0.003) in the ON state.

Conclusion: Cognitive dysfunctions are directly related to gait instability in PD, reinforcing the importance of interventions that integrate motor and cognitive rehabilitation. These strategies can improve gait safety and efficacy in individuals with PD.

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来源期刊
Dementia e Neuropsychologia
Dementia e Neuropsychologia Medicine-Geriatrics and Gerontology
CiteScore
2.20
自引率
0.00%
发文量
58
审稿时长
8 weeks
期刊介绍: Dementia top Neuropsychologia the official scientific journal of the Cognitive Neurology and Ageing Department of the Brazilian Academy of Neurology and of the Brazilian Association of Geriatric Neuropsychiatry, is published by the "Associação Neurologia Cognitiva e do Comportamento", a nonprofit Brazilian association. Regularly published on March, June, September, and December since 2007.
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