Ahmed S Elwehidy, Amr Mohammed Elsayed Abdelkader, Sherein M Hagras, Nada M GabAllah, Mostafa As Elwehidy, Dina Abdelfattah
{"title":"黏液-环周-缝合-小梁切开术联合超声乳化与单纯超声乳化治疗慢性原发性闭角型青光眼。","authors":"Ahmed S Elwehidy, Amr Mohammed Elsayed Abdelkader, Sherein M Hagras, Nada M GabAllah, Mostafa As Elwehidy, Dina Abdelfattah","doi":"10.1186/s12886-025-04373-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To assess the surgical outcomes of visco-circumferential-suture-trabeculotomy-synechiolysis (VCSTS) with phacoemulsification compared with phacoemulsification alone for the treatment of chronic primary angle closure glaucoma (PACG).</p><p><strong>Settings: </strong>Mansoura Ophthalmic Center, Mansoura, Egypt.</p><p><strong>Design: </strong>Retrospective double armed interventional non randomized comparative study.</p><p><strong>Methods: </strong>A total of 88 eyes (69 patients) with uncontrolled PACG between 2016 and 2022 were subjected to VCSTS with phacoemulsification (Group 1) or phacoemulsification (PE) alone (Group 2). The follow-up period was 24 months. Success was defined as an IOP between 6 and 18 mmHg, with a reduction of at least 30% from baseline with (qualified) or without (complete) antiglaucoma medications (AGMs).</p><p><strong>Results: </strong>The mean ± standard deviation ages of the study patients in groups 1 and 2 were 61.1±0.9 and 61.7±0.8 years (p=0.536), respectively. The means ± standard deviations of the preoperative and final postoperative IOP and AGM in groups 1 and 2 were 27.46±0.32 and 28.0±0.3 and 14.15±1.1 and 16.7±0.71 mmHg, respectively (p<0.001), and 3.18±0.07 and 3.2±0.9 and 0.47±1.1 and 1.1±1.5, respectively (p=0.035). The rates of complete success (Kaplan‒Meier) in groups 1 and 2 were 95.3% and 86.7%, respectively (p=0.153). Mild self-limited hyphema was the most common complication in Group 1, with no serious complications reported in Group 2.</p><p><strong>Conclusions: </strong>Phacoemulsification results in a significant and sustained reduction in IOP and the need for AGMs for at least 2 years of follow-up. The addition of VCSTS to phacoemulsification provides a greater reduction in IOP and AGMs and improved surgical success without serious complications.</p>","PeriodicalId":9058,"journal":{"name":"BMC Ophthalmology","volume":"25 1","pages":"503"},"PeriodicalIF":1.7000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439390/pdf/","citationCount":"0","resultStr":"{\"title\":\"Visco-circumferential-suture-trabeculotomy-synechiolysis with phacoemulsification versus phacoemulsification alone for chronic primary angle closure glaucoma.\",\"authors\":\"Ahmed S Elwehidy, Amr Mohammed Elsayed Abdelkader, Sherein M Hagras, Nada M GabAllah, Mostafa As Elwehidy, Dina Abdelfattah\",\"doi\":\"10.1186/s12886-025-04373-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To assess the surgical outcomes of visco-circumferential-suture-trabeculotomy-synechiolysis (VCSTS) with phacoemulsification compared with phacoemulsification alone for the treatment of chronic primary angle closure glaucoma (PACG).</p><p><strong>Settings: </strong>Mansoura Ophthalmic Center, Mansoura, Egypt.</p><p><strong>Design: </strong>Retrospective double armed interventional non randomized comparative study.</p><p><strong>Methods: </strong>A total of 88 eyes (69 patients) with uncontrolled PACG between 2016 and 2022 were subjected to VCSTS with phacoemulsification (Group 1) or phacoemulsification (PE) alone (Group 2). The follow-up period was 24 months. Success was defined as an IOP between 6 and 18 mmHg, with a reduction of at least 30% from baseline with (qualified) or without (complete) antiglaucoma medications (AGMs).</p><p><strong>Results: </strong>The mean ± standard deviation ages of the study patients in groups 1 and 2 were 61.1±0.9 and 61.7±0.8 years (p=0.536), respectively. The means ± standard deviations of the preoperative and final postoperative IOP and AGM in groups 1 and 2 were 27.46±0.32 and 28.0±0.3 and 14.15±1.1 and 16.7±0.71 mmHg, respectively (p<0.001), and 3.18±0.07 and 3.2±0.9 and 0.47±1.1 and 1.1±1.5, respectively (p=0.035). The rates of complete success (Kaplan‒Meier) in groups 1 and 2 were 95.3% and 86.7%, respectively (p=0.153). Mild self-limited hyphema was the most common complication in Group 1, with no serious complications reported in Group 2.</p><p><strong>Conclusions: </strong>Phacoemulsification results in a significant and sustained reduction in IOP and the need for AGMs for at least 2 years of follow-up. The addition of VCSTS to phacoemulsification provides a greater reduction in IOP and AGMs and improved surgical success without serious complications.</p>\",\"PeriodicalId\":9058,\"journal\":{\"name\":\"BMC Ophthalmology\",\"volume\":\"25 1\",\"pages\":\"503\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439390/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12886-025-04373-5\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12886-025-04373-5","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Visco-circumferential-suture-trabeculotomy-synechiolysis with phacoemulsification versus phacoemulsification alone for chronic primary angle closure glaucoma.
Purpose: To assess the surgical outcomes of visco-circumferential-suture-trabeculotomy-synechiolysis (VCSTS) with phacoemulsification compared with phacoemulsification alone for the treatment of chronic primary angle closure glaucoma (PACG).
Settings: Mansoura Ophthalmic Center, Mansoura, Egypt.
Design: Retrospective double armed interventional non randomized comparative study.
Methods: A total of 88 eyes (69 patients) with uncontrolled PACG between 2016 and 2022 were subjected to VCSTS with phacoemulsification (Group 1) or phacoemulsification (PE) alone (Group 2). The follow-up period was 24 months. Success was defined as an IOP between 6 and 18 mmHg, with a reduction of at least 30% from baseline with (qualified) or without (complete) antiglaucoma medications (AGMs).
Results: The mean ± standard deviation ages of the study patients in groups 1 and 2 were 61.1±0.9 and 61.7±0.8 years (p=0.536), respectively. The means ± standard deviations of the preoperative and final postoperative IOP and AGM in groups 1 and 2 were 27.46±0.32 and 28.0±0.3 and 14.15±1.1 and 16.7±0.71 mmHg, respectively (p<0.001), and 3.18±0.07 and 3.2±0.9 and 0.47±1.1 and 1.1±1.5, respectively (p=0.035). The rates of complete success (Kaplan‒Meier) in groups 1 and 2 were 95.3% and 86.7%, respectively (p=0.153). Mild self-limited hyphema was the most common complication in Group 1, with no serious complications reported in Group 2.
Conclusions: Phacoemulsification results in a significant and sustained reduction in IOP and the need for AGMs for at least 2 years of follow-up. The addition of VCSTS to phacoemulsification provides a greater reduction in IOP and AGMs and improved surgical success without serious complications.
期刊介绍:
BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.