{"title":"急性脑损伤的最新进展","authors":"Chiara Robba, Sarah Wahlster, Virginia Newcombe","doi":"10.1007/s00134-025-08121-7","DOIUrl":null,"url":null,"abstract":"Despite recent advances in understanding and managing acute brain injury (ABI), it remains a major contributor to mortality and disability worldwide. As there are currently no interventions available to reverse the primary injury, ABI management in the intensive care unit (ICU) is mainly focused on minimising secondary brain damage [1]. Given the heterogeneous pathophysiologies involved in ABI, a shift towards individualised care based on disease endotype and phenotype is warranted to improve outcomes. In this manuscript, we summarise key aspects of the latest evidence on ABI management in the ICU.","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"78 1","pages":""},"PeriodicalIF":21.2000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Update on acute brain injury\",\"authors\":\"Chiara Robba, Sarah Wahlster, Virginia Newcombe\",\"doi\":\"10.1007/s00134-025-08121-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Despite recent advances in understanding and managing acute brain injury (ABI), it remains a major contributor to mortality and disability worldwide. As there are currently no interventions available to reverse the primary injury, ABI management in the intensive care unit (ICU) is mainly focused on minimising secondary brain damage [1]. Given the heterogeneous pathophysiologies involved in ABI, a shift towards individualised care based on disease endotype and phenotype is warranted to improve outcomes. In this manuscript, we summarise key aspects of the latest evidence on ABI management in the ICU.\",\"PeriodicalId\":13665,\"journal\":{\"name\":\"Intensive Care Medicine\",\"volume\":\"78 1\",\"pages\":\"\"},\"PeriodicalIF\":21.2000,\"publicationDate\":\"2025-09-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Intensive Care Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00134-025-08121-7\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Intensive Care Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00134-025-08121-7","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Despite recent advances in understanding and managing acute brain injury (ABI), it remains a major contributor to mortality and disability worldwide. As there are currently no interventions available to reverse the primary injury, ABI management in the intensive care unit (ICU) is mainly focused on minimising secondary brain damage [1]. Given the heterogeneous pathophysiologies involved in ABI, a shift towards individualised care based on disease endotype and phenotype is warranted to improve outcomes. In this manuscript, we summarise key aspects of the latest evidence on ABI management in the ICU.
期刊介绍:
Intensive Care Medicine is the premier publication platform fostering the communication and exchange of cutting-edge research and ideas within the field of intensive care medicine on a comprehensive scale. Catering to professionals involved in intensive medical care, including intensivists, medical specialists, nurses, and other healthcare professionals, ICM stands as the official journal of The European Society of Intensive Care Medicine. ICM is dedicated to advancing the understanding and practice of intensive care medicine among professionals in Europe and beyond. The journal provides a robust platform for disseminating current research findings and innovative ideas in intensive care medicine. Content published in Intensive Care Medicine encompasses a wide range, including review articles, original research papers, letters, reviews, debates, and more.