模拟风湿病的淋巴增生性疾病:临床推理的观点。

IF 4.6 2区 医学 Q1 ALLERGY
Jeffrey Z Shen, Eric D Carlsen, Luis F Carrillo, Dahima Cintron, Ben Kellogg, Jamie Lim, Matilda Nicholas, Elijah Lackey, John Dasher
{"title":"模拟风湿病的淋巴增生性疾病:临床推理的观点。","authors":"Jeffrey Z Shen, Eric D Carlsen, Luis F Carrillo, Dahima Cintron, Ben Kellogg, Jamie Lim, Matilda Nicholas, Elijah Lackey, John Dasher","doi":"10.1007/s11882-025-01220-x","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Lymphoproliferative disorders encompass a variety of hematologic diseases that are increasingly recognized. Patients with these conditions may present to rheumatologists or other specialists prior to a hematologist-oncologist. This review is intended to highlight key distinguishing features between rheumatologic conditions and lymphoproliferative disorders, and suggest diagnostic approaches.</p><p><strong>Recent findings: </strong>Recent studies have shown that lymphoproliferative diseases can mimic rheumatologic disease, and differentiation is complex. Advances in imaging techniques such as FDG PET/CT, and improved understanding of lymph node histopathology have improved diagnostic accuracy. Attention to specific details such as the pattern of organ involvement, the presence or absence of key clinical features, and the consistency of treatment response can assist in accurate diagnosis. Our review highlights the importance of considering lymphoproliferative disorders in the differential diagnosis of rheumatologic disease. A thorough clinical history, targeted biopsies, and collaboration with hematopathologists are essential for timely diagnosis and care. Future research should concentrate on identifying biomarkers and formulating diagnostic algorithms to aid in differentiating lymphoproliferative disorders from autoimmune diseases, which will ultimately improve patient outcomes.</p>","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"25 1","pages":"38"},"PeriodicalIF":4.6000,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective.\",\"authors\":\"Jeffrey Z Shen, Eric D Carlsen, Luis F Carrillo, Dahima Cintron, Ben Kellogg, Jamie Lim, Matilda Nicholas, Elijah Lackey, John Dasher\",\"doi\":\"10.1007/s11882-025-01220-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose of review: </strong>Lymphoproliferative disorders encompass a variety of hematologic diseases that are increasingly recognized. Patients with these conditions may present to rheumatologists or other specialists prior to a hematologist-oncologist. This review is intended to highlight key distinguishing features between rheumatologic conditions and lymphoproliferative disorders, and suggest diagnostic approaches.</p><p><strong>Recent findings: </strong>Recent studies have shown that lymphoproliferative diseases can mimic rheumatologic disease, and differentiation is complex. Advances in imaging techniques such as FDG PET/CT, and improved understanding of lymph node histopathology have improved diagnostic accuracy. Attention to specific details such as the pattern of organ involvement, the presence or absence of key clinical features, and the consistency of treatment response can assist in accurate diagnosis. Our review highlights the importance of considering lymphoproliferative disorders in the differential diagnosis of rheumatologic disease. A thorough clinical history, targeted biopsies, and collaboration with hematopathologists are essential for timely diagnosis and care. Future research should concentrate on identifying biomarkers and formulating diagnostic algorithms to aid in differentiating lymphoproliferative disorders from autoimmune diseases, which will ultimately improve patient outcomes.</p>\",\"PeriodicalId\":55198,\"journal\":{\"name\":\"Current Allergy and Asthma Reports\",\"volume\":\"25 1\",\"pages\":\"38\"},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2025-09-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Allergy and Asthma Reports\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s11882-025-01220-x\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ALLERGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Allergy and Asthma Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11882-025-01220-x","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ALLERGY","Score":null,"Total":0}
引用次数: 0

摘要

综述目的:淋巴细胞增生性疾病包括多种血液系统疾病,目前越来越被认识到。患有这些疾病的患者可能会在血液学肿瘤学家之前先向风湿病学家或其他专家就诊。本综述旨在强调风湿病和淋巴增生性疾病之间的关键区别特征,并提出诊断方法。最近的发现:最近的研究表明,淋巴增生性疾病可以模仿风湿病,并区分是复杂的。成像技术的进步,如FDG PET/CT,以及对淋巴结组织病理学的理解的提高,提高了诊断的准确性。注意特定的细节,如器官受累的模式,关键临床特征的存在或不存在,以及治疗反应的一致性可以帮助准确诊断。我们的综述强调了在风湿病鉴别诊断中考虑淋巴增生性疾病的重要性。全面的临床病史、有针对性的活组织检查以及与血液病理学家的合作对于及时诊断和护理至关重要。未来的研究应集中在识别生物标志物和制定诊断算法,以帮助区分淋巴增生性疾病与自身免疫性疾病,这将最终改善患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective.

Purpose of review: Lymphoproliferative disorders encompass a variety of hematologic diseases that are increasingly recognized. Patients with these conditions may present to rheumatologists or other specialists prior to a hematologist-oncologist. This review is intended to highlight key distinguishing features between rheumatologic conditions and lymphoproliferative disorders, and suggest diagnostic approaches.

Recent findings: Recent studies have shown that lymphoproliferative diseases can mimic rheumatologic disease, and differentiation is complex. Advances in imaging techniques such as FDG PET/CT, and improved understanding of lymph node histopathology have improved diagnostic accuracy. Attention to specific details such as the pattern of organ involvement, the presence or absence of key clinical features, and the consistency of treatment response can assist in accurate diagnosis. Our review highlights the importance of considering lymphoproliferative disorders in the differential diagnosis of rheumatologic disease. A thorough clinical history, targeted biopsies, and collaboration with hematopathologists are essential for timely diagnosis and care. Future research should concentrate on identifying biomarkers and formulating diagnostic algorithms to aid in differentiating lymphoproliferative disorders from autoimmune diseases, which will ultimately improve patient outcomes.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
11.20
自引率
1.80%
发文量
21
审稿时长
6-12 weeks
期刊介绍: The aim of Current Allergy and Asthma Reports is to systematically provide the views of highly selected experts on current advances in the fields of allergy and asthma and highlight the most important papers recently published. All reviews are intended to facilitate the understanding of new advances in science for better diagnosis, treatment, and prevention of allergy and asthma. We accomplish this aim by appointing international experts in major subject areas across the discipline to review select topics emphasizing recent developments and highlighting important new papers and emerging concepts. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Over a one- to two-year period, readers are updated on all the major advances in allergy and asthma.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信