气管内管填塞压迫缝合治疗完全性前置胎盘出血的回顾性研究。

IF 2.4 3区 医学 Q2 OBSTETRICS & GYNECOLOGY
Xi-Shi Lin, Xiao-Xing Zhang, Jie Chen, Ling-Li Ning, Li-Yuan Zhang, Ying Jiang, Wei-Miao Yao, Bai-Hui Zhao, Qiong Luo
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引用次数: 0

摘要

目的:我们的研究开发了气管内管填塞的横向平行压缩缝合(TPCS),假设其横向压缩设计可以增强止血,特别是在胎盘增生谱(PAS)病例中。方法:在2022年1月1日至2024年12月31日期间,346名患有完全性前置胎盘的妇女参加了这项研究。为了最大限度地减少选择偏差并控制潜在的联合创始人,我们使用1:1最近邻算法进行倾向评分匹配(PSM),卡尺宽度为0.02。匹配的队列(53例TPCS与53例子宫填充物对照)显示平衡的基线特征。收集相关结果,如手术时间、估计失血量、输血需求和住院时间。其他数据包括子宫强直、术后疼痛程度、再手术率和新生儿结局。结果:TPCS组手术时间明显缩短(59.62±27.04 min vs. 73.87±26.28 min, P = 0.007),术中出血量明显减少(792.45±892.46 mL vs. 1220.75±1090.93 mL, P = 0.029)。TPCS的住院时间较短(6.10±2.06天vs. 7.49±3.29天,P = 0.003),再手术率较低(3.8% vs. 60.4%, P = 0.003)。结论:经过严格的PSM调整后,TPCS在前置胎盘处理中表现出比子宫填塞更强的围手术期安全性和恢复优势,支持临床应用。它的简单性和低资源需求突出了在不同环境中的潜在效用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transverse parallel compression suture with endotracheal tube tamponade for management of hemorrhage in complete placenta previa: A retrospective study.

Objective: Our study developed the Transverse Parallel Compression Suture (TPCS) with endotracheal tube tamponade, hypothesizing that its transverse compression design would enhance hemostasis, particularly in placenta accreta spectrum (PAS) cases.

Methods: Between January 1, 2022, and December 31, 2024, 346 women with complete placenta previa were enrolled in this study. To minimize selection bias and control for potential con-founders, we performed propensity score matching (PSM) using a 1:1 nearest-neighbor algorithm with a caliper width of 0.02. The matched cohorts (53 TPCS cases vs. 53 uterine packing controls) demonstrated balanced baseline characteristics. Relevant outcomes, such as operative duration, estimated blood loss, transfusion needs, and hospital stays were collected. Additional data included the uterotonics, postoperative pain levels, re-operation rate, and newborn outcomes.

Results: The results showed that the TPCS group had significantly shorter operative time (59.62 ± 27.04 min vs. 73.87 ± 26.28 min, P = 0.007), reduced intraoperative blood loss (792.45 ± 892.46 mL vs. 1220.75 ± 1090.93 mL, P = 0.029). Also, TPCS was associated with shorter hospitalization (6.10 ± 2.06 vs. 7.49 ± 3.29 days, P = 0.003) and markedly lower reoperation rates (3.8% vs. 60.4%, P < 0.001). TPCS was associated with markedly improved pain management, with 96.2% of patients reporting mild pain (Visual Analogue Scale less than 4) versus 18.9% in the packing group (P < 0.001), alongside an 84% relative reduction in analgesic use (11.3% vs. 71.7%, P < 0.001). Besides, Neonatally, TPCS showed lower NICU admissions (34.0% vs. 56.6%, P = 0.031) with comparable Apgar scores and birth weights.

Conclusion: After rigorous PSM adjustment, TPCS demonstrated superior perioperative safety and recovery advantages over uterine packing in placenta previa management, supporting its adoption in clinical practice. Its simplicity and low resource demand highlight potential utility in diverse settings.

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来源期刊
CiteScore
5.80
自引率
2.60%
发文量
493
审稿时长
3-6 weeks
期刊介绍: The International Journal of Gynecology & Obstetrics publishes articles on all aspects of basic and clinical research in the fields of obstetrics and gynecology and related subjects, with emphasis on matters of worldwide interest.
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