内镜设置对食管食物嵌塞患者预后的“后小时”效应和作用。

IF 2.5 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Neha Wadhavkar, Breton Roussel, Joao Filipe Monteiro, Kanwal Bains, Kuntal Bhowmick, Mouhand Mohamed, Markos Kalligeros, Sean Fine
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引用次数: 0

摘要

背景和目的:食管食物嵌塞(EFI)导致的梗阻是一种胃肠道急症,需要通过上消化道内窥镜去除嵌塞。目前的指南建议在24小时内进行紧急干预,以减少并发症的风险。然而,关于影响实践模式的具体因素的数据有限,包括内镜下EFI干预的时间和设置。方法:我们对2015-2021年在三家医院急诊科(ED)就诊的684例EFI患者进行了回顾性分析。447例患者符合纳入标准。我们比较了住院率、急诊科分诊到内窥镜检查时间、镇静类型、内窥镜检查设置[急诊科/重症监护室(ICU)、手术室(OR)或内窥镜检查单元(EU)]以及“营业时间”(上午8点至下午5点)和“下班时间”(周末或上午8点之前/下午5点之后)的并发症。结果:在509例EFI病例中,67.2%是在“下班后”进行的,56.2%发生在欧盟。“数小时后”内窥镜检查涉及中度镇静的可能性超过4倍(OR 4.35[1.64-11.54])。在“营业时间”的病例中,从急诊室分诊到内窥镜检查的平均时间明显更长(11.3±21.2 h vs 5.4±10.3 h,校正p值= 0.0002)。“数小时后”接受内窥镜检查的患者住院的可能性降低74%(0.26[0.13-0.55])。虽然没有统计学意义,但与“营业时间”相比,“下班时间”病例的并发症发生率(2.3比4.8%)和住院死亡率(0.0%比1.2%)较低(p值分别≤0.1367和≤0.1072)。结论:我们发现,与目前的文献相反,EFI的“下班后”内窥镜脱嵌术与“营业时间”相比没有增加住院率或增加并发症。我们的研究结果强调了EFI“小时后”内窥镜干预的安全性、有效性和可行性,这可能有助于制定资源分配和医院方案,以改善患者未来的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The "After Hours" Effect and Role of Endoscopy Setting on Outcomes in Patients with Esophageal Food Impaction.

Background and aims: Esophageal food impaction (EFI) resulting in obstruction is a gastrointestinal emergency requiring disimpaction by upper endoscopy. Current guidelines recommend emergent intervention within 24 h to reduce risk of complications. However, limited data exist regarding specific factors affecting practice patterns, including timing and setting of endoscopic intervention for EFI.

Methods: We conducted a retrospective review of 684 patients who presented with EFI to the emergency department (ED) at three hospitals from 2015-2021. 447 patients met inclusion criteria. We compared hospitalization rates, ED triage-to-endoscopy time, sedation type, endoscopy setting [ED/intensive care unit (ICU), operating room (OR), or endoscopy unit (EU)], and complications for "business hours" (between 8AM and 5PM) and "after hours" procedures (weekends or before 8AM/after 5PM).

Results: Among 509 EFI cases, 67.2% were performed "after hours," and 56.2% occurred in the EU. "After hours" endoscopies were over fourfold more likely to involve moderate sedation (OR 4.35 [1.64-11.54]). Mean ED triage-to-endoscopy time was significantly longer for "business hours" cases (11.3 ± 21.2 h versus 5.4 ± 10.3 h, adjusted p-value = 0.0002). Patients undergoing endoscopy "after hours" were 74% less likely to be hospitalized (0.26 [0.13-0.55]). Although not statistically significant, "after hours" cases had lower complication rates (2.3 versus 4.8%) and in-hospital mortality (0.0% vs 1.2%) compared to "business hours" (p-value ≤ 0.1367 and ≤ 0.1072, respectively).

Conclusions: We found that "after hours" endoscopic disimpactions for EFI did not have increased hospitalizations or increased complications relative to "business hours," contrary to current literature. Our findings underscore the safety, efficacy, and feasibility of "after hours" endoscopic intervention for EFI, which may help shape resource allocation and hospital protocols to improve patient outcomes in the future.

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来源期刊
Digestive Diseases and Sciences
Digestive Diseases and Sciences 医学-胃肠肝病学
CiteScore
6.40
自引率
3.20%
发文量
420
审稿时长
1 months
期刊介绍: Digestive Diseases and Sciences publishes high-quality, peer-reviewed, original papers addressing aspects of basic/translational and clinical research in gastroenterology, hepatology, and related fields. This well-illustrated journal features comprehensive coverage of basic pathophysiology, new technological advances, and clinical breakthroughs; insights from prominent academicians and practitioners concerning new scientific developments and practical medical issues; and discussions focusing on the latest changes in local and worldwide social, economic, and governmental policies that affect the delivery of care within the disciplines of gastroenterology and hepatology.
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