接种TAK-003登革热疫苗后出现严重登革出血热：一例潜在的疫苗相关不良反应报告

IF 4.3 2区医学 Q1 INFECTIOUS DISEASES

International Journal of Infectious Diseases Pub Date : 2025-09-12 DOI:10.1016/j.ijid.2025.108062

Pinyo Rattanaumpawan, Navin Horthongkham, Kamol Suwannakarn, Artittaya Athipanyasilp, Ubonvan Jongwutiwes

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引用次数: 0

摘要

我们报告一例在接种tak -003（武田登革热疫苗）5天后出现症状的严重登革热病例。全基因组测序证实，所有四种登革热血清型均与疫苗株高度相似，特别是DENV-2。这一发现值得进一步调查其与疫苗不良事件的潜在关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Severe dengue hemorrhagic fever after TAK-003 dengue vaccination: A case report of a potential vaccine-associated adverse reaction.

We report a severe dengue case that developed symptoms 5 days post-TAK-003 dengue vaccine administration. Whole-genome sequencing confirmed co-detection of all four dengue serotypes with high similarity to vaccine strains, especially DENV-2. This finding warrants further investigation into a potential association with vaccine adverse events.

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来源期刊

International Journal of Infectious Diseases 医学-传染病学

CiteScore

18.90

自引率

2.40%

发文量

1020

审稿时长

30 days

期刊介绍： International Journal of Infectious Diseases (IJID) Publisher: International Society for Infectious Diseases Publication Frequency: Monthly Type: Peer-reviewed, Open Access Scope: Publishes original clinical and laboratory-based research. Reports clinical trials, reviews, and some case reports. Focuses on epidemiology, clinical diagnosis, treatment, and control of infectious diseases. Emphasizes diseases common in under-resourced countries.