凤凰脓毒症评分评估:2020-2024年不同初级状态和年龄儿童队列的特征

IF 3 3区 医学 Q2 INFECTIOUS DISEASES
Wanyu Jia, Ruiyang Sun, Jiapu Hou, Zewen Ding, Peng Li, Chunlan Song
{"title":"凤凰脓毒症评分评估:2020-2024年不同初级状态和年龄儿童队列的特征","authors":"Wanyu Jia, Ruiyang Sun, Jiapu Hou, Zewen Ding, Peng Li, Chunlan Song","doi":"10.1007/s10096-025-05255-w","DOIUrl":null,"url":null,"abstract":"<p><p>The purpose was to validate the applicability of the Phoenix Sepsis Score and to compare it with other scores. The applicability of the Phoenix Sepsis Score in children with different primary statuses and age groups was compared. This study is a retrospective study. Children aged between 1 month and 18 years with a clinically suspected diagnosis of sepsis from January 2020 to December 2024 were selected for the study. Clinical data were collected and Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment, and Pediatric Logistic Organ Dysfunction Score-2 scores were calculated. The predictive values were assessed using the receiver operator characteristic curve. Compare the area under the curve of different receiver operator characteristic curves. A total of 341 children were included, of which 203 were Male, with a median age of 32 months. There were 103 children with primary diseases. Based on the Phoenix Sepsis Score, 174patients were diagnosed with sepsis. All three scores were significantly higher in the death group. The areas under the curve of the Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores for death in children with suspected sepsis were 0.874(0.834,0.907), 0.884(0.846,0.923) and 0.867(0.826,0.901), respectively. There were no statistically significant differences between the three scores in terms of predictive value. The area under the curve of Phoenix Sepsis Score for death in all age groups from 1 month to 11 years old were greater than 0.808(0.700,0.890). The areas under the curve of the Phoenix Sepsis Score for death in children with or without primary diseases were 0.790(0.699,0.864) and 0.894(0.839,0.949), respectively. The Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores had high predictive value for mortality in children with suspected sepsis. The Phoenix Sepsis Score had good predictive value in children at different primary states and different age. The predictive value of the Phoenix Sepsis Score was lower in children with primary disease.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Assessment of Phoenix sepsis score: characterization of a cohort of children of different primary statuses and ages, 2020-2024.\",\"authors\":\"Wanyu Jia, Ruiyang Sun, Jiapu Hou, Zewen Ding, Peng Li, Chunlan Song\",\"doi\":\"10.1007/s10096-025-05255-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The purpose was to validate the applicability of the Phoenix Sepsis Score and to compare it with other scores. The applicability of the Phoenix Sepsis Score in children with different primary statuses and age groups was compared. This study is a retrospective study. Children aged between 1 month and 18 years with a clinically suspected diagnosis of sepsis from January 2020 to December 2024 were selected for the study. Clinical data were collected and Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment, and Pediatric Logistic Organ Dysfunction Score-2 scores were calculated. The predictive values were assessed using the receiver operator characteristic curve. Compare the area under the curve of different receiver operator characteristic curves. A total of 341 children were included, of which 203 were Male, with a median age of 32 months. There were 103 children with primary diseases. Based on the Phoenix Sepsis Score, 174patients were diagnosed with sepsis. All three scores were significantly higher in the death group. The areas under the curve of the Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores for death in children with suspected sepsis were 0.874(0.834,0.907), 0.884(0.846,0.923) and 0.867(0.826,0.901), respectively. There were no statistically significant differences between the three scores in terms of predictive value. The area under the curve of Phoenix Sepsis Score for death in all age groups from 1 month to 11 years old were greater than 0.808(0.700,0.890). The areas under the curve of the Phoenix Sepsis Score for death in children with or without primary diseases were 0.790(0.699,0.864) and 0.894(0.839,0.949), respectively. The Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores had high predictive value for mortality in children with suspected sepsis. The Phoenix Sepsis Score had good predictive value in children at different primary states and different age. The predictive value of the Phoenix Sepsis Score was lower in children with primary disease.</p>\",\"PeriodicalId\":11782,\"journal\":{\"name\":\"European Journal of Clinical Microbiology & Infectious Diseases\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Clinical Microbiology & Infectious Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10096-025-05255-w\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Clinical Microbiology & Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10096-025-05255-w","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0

摘要

目的是验证凤凰脓毒症评分的适用性,并将其与其他评分进行比较。比较凤凰脓毒症评分在不同原发状态和年龄组儿童中的适用性。本研究为回顾性研究。研究选择了2020年1月至2024年12月期间临床疑似败血症诊断的年龄在1个月至18岁之间的儿童。收集临床资料,计算Phoenix败血症评分、儿科序事性器官衰竭评分和儿科Logistic器官功能障碍评分-2分。使用接收算子特征曲线评估预测值。比较不同接收算子特征曲线下的面积。共纳入341例患儿,其中男性203例,中位年龄32个月。有103名儿童患有原发疾病。根据Phoenix脓毒症评分,174例患者被诊断为脓毒症。死亡组的这三个分数都明显更高。怀疑脓毒症患儿死亡的凤凰脓毒症评分曲线下面积为0.874(0.834,0.907),儿童序期器官功能衰竭评分曲线下面积为0.884(0.846,0.923),儿童Logistic器官功能障碍评分-2评分曲线下面积为0.867(0.826,0.901)。三种评分在预测价值方面无统计学差异。各年龄组1个月~ 11岁死亡凤凰脓毒症评分曲线下面积均大于0.808(0.700,0.890)。有无原发疾病患儿死亡的凤凰脓毒症评分曲线下面积分别为0.790(0.699,0.864)和0.894(0.839,0.949)。Phoenix脓毒症评分、儿科序贯器官衰竭评估和儿科Logistic器官功能障碍评分-2评分对疑似脓毒症患儿的死亡率具有较高的预测价值。凤凰脓毒症评分对不同初级阶段和不同年龄的儿童有较好的预测价值。凤凰脓毒症评分在有原发疾病的儿童中预测价值较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Phoenix sepsis score: characterization of a cohort of children of different primary statuses and ages, 2020-2024.

The purpose was to validate the applicability of the Phoenix Sepsis Score and to compare it with other scores. The applicability of the Phoenix Sepsis Score in children with different primary statuses and age groups was compared. This study is a retrospective study. Children aged between 1 month and 18 years with a clinically suspected diagnosis of sepsis from January 2020 to December 2024 were selected for the study. Clinical data were collected and Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment, and Pediatric Logistic Organ Dysfunction Score-2 scores were calculated. The predictive values were assessed using the receiver operator characteristic curve. Compare the area under the curve of different receiver operator characteristic curves. A total of 341 children were included, of which 203 were Male, with a median age of 32 months. There were 103 children with primary diseases. Based on the Phoenix Sepsis Score, 174patients were diagnosed with sepsis. All three scores were significantly higher in the death group. The areas under the curve of the Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores for death in children with suspected sepsis were 0.874(0.834,0.907), 0.884(0.846,0.923) and 0.867(0.826,0.901), respectively. There were no statistically significant differences between the three scores in terms of predictive value. The area under the curve of Phoenix Sepsis Score for death in all age groups from 1 month to 11 years old were greater than 0.808(0.700,0.890). The areas under the curve of the Phoenix Sepsis Score for death in children with or without primary diseases were 0.790(0.699,0.864) and 0.894(0.839,0.949), respectively. The Phoenix Sepsis Score, paediatric Sequential Organ Failure Assessment and Pediatric Logistic Organ Dysfunction Score-2 scores had high predictive value for mortality in children with suspected sepsis. The Phoenix Sepsis Score had good predictive value in children at different primary states and different age. The predictive value of the Phoenix Sepsis Score was lower in children with primary disease.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
10.40
自引率
2.20%
发文量
138
审稿时长
1 months
期刊介绍: EJCMID is an interdisciplinary journal devoted to the publication of communications on infectious diseases of bacterial, viral and parasitic origin.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信