{"title":"自体股骨头结构植骨联合全髋关节置换术治疗成人Crowe II/III型发育不良的临床疗效及预后分析","authors":"Chengyu Li, Fang Pei, Feng Wan, Baiyi Meng","doi":"10.62347/TUYG1784","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical efficacy and mid-term outcomes of total hip arthroplasty (THA) assisted by acetabular reconstruction using autologous femoral head structural bone grafting in patients with Crowe type II/III developmental dysplasia of the hip (DDH).</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 100 patients (100 hips) with Crowe type II/III DDH who underwent THA at the Affiliated Hospital of Xuzhou Medical University between January 2019 and December 2022. All patients received autologous femoral head structural bone grafting for acetabular reconstruction during the procedure. Perioperative parameters, visual analogue scale (VAS) scores, limb length discrepancy (LLD), range of motion (ROM), hip function [Harris hip score and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)], incidence of complications, quality of life [Generic Quality of Life Inventory-74 (GQOLI-74)], and radiographic outcomes were assessed.</p><p><strong>Results: </strong>The mean follow-up duration was 10.78 ± 1.65 months. Postoperatively, the VAS score significantly decreased from 6.52 ± 2.58 to 1.73 ± 0.72 (P < 0.001), and the LLD reduced from 2.88 ± 0.54 cm to 0.92 ± 0.39 cm (P < 0.001). The Harris hip score increased from 58.23 ± 6.14 to 92.45 ± 5.82 (P < 0.001), while the WOMAC score decreased from 72.54 ± 8.61 to 18.34 ± 5.09 (P < 0.001). All domains of the GQOLI-74 score showed significant improvements (P < 0.001). The overall complication rate was 1.0%, and radiographic assessments confirmed bone healing.</p><p><strong>Conclusion: </strong>THA assisted by autologous femoral head structural bone grafting is a safe and effective approach for treating Crowe type II/III DDH. It significantly enhances hip function, restores biomechanics, improves the quality of life, and is associated with a low complication rate and favorable mid-term outcomes.</p>","PeriodicalId":7731,"journal":{"name":"American journal of translational research","volume":"17 8","pages":"5987-5998"},"PeriodicalIF":1.6000,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432698/pdf/","citationCount":"0","resultStr":"{\"title\":\"Clinical efficacy and prognostic analysis of autologous femoral head structural bone grafting combined with total hip arthroplasty for Crowe Type II/III developmental dysplasia of the hip in adults.\",\"authors\":\"Chengyu Li, Fang Pei, Feng Wan, Baiyi Meng\",\"doi\":\"10.62347/TUYG1784\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the clinical efficacy and mid-term outcomes of total hip arthroplasty (THA) assisted by acetabular reconstruction using autologous femoral head structural bone grafting in patients with Crowe type II/III developmental dysplasia of the hip (DDH).</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 100 patients (100 hips) with Crowe type II/III DDH who underwent THA at the Affiliated Hospital of Xuzhou Medical University between January 2019 and December 2022. All patients received autologous femoral head structural bone grafting for acetabular reconstruction during the procedure. Perioperative parameters, visual analogue scale (VAS) scores, limb length discrepancy (LLD), range of motion (ROM), hip function [Harris hip score and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)], incidence of complications, quality of life [Generic Quality of Life Inventory-74 (GQOLI-74)], and radiographic outcomes were assessed.</p><p><strong>Results: </strong>The mean follow-up duration was 10.78 ± 1.65 months. Postoperatively, the VAS score significantly decreased from 6.52 ± 2.58 to 1.73 ± 0.72 (P < 0.001), and the LLD reduced from 2.88 ± 0.54 cm to 0.92 ± 0.39 cm (P < 0.001). The Harris hip score increased from 58.23 ± 6.14 to 92.45 ± 5.82 (P < 0.001), while the WOMAC score decreased from 72.54 ± 8.61 to 18.34 ± 5.09 (P < 0.001). All domains of the GQOLI-74 score showed significant improvements (P < 0.001). The overall complication rate was 1.0%, and radiographic assessments confirmed bone healing.</p><p><strong>Conclusion: </strong>THA assisted by autologous femoral head structural bone grafting is a safe and effective approach for treating Crowe type II/III DDH. It significantly enhances hip function, restores biomechanics, improves the quality of life, and is associated with a low complication rate and favorable mid-term outcomes.</p>\",\"PeriodicalId\":7731,\"journal\":{\"name\":\"American journal of translational research\",\"volume\":\"17 8\",\"pages\":\"5987-5998\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-08-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432698/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of translational research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.62347/TUYG1784\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of translational research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.62347/TUYG1784","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0
摘要
目的:评价自体股骨头结构骨移植全髋关节置换术(THA)辅助髋臼重建治疗Crowe II/III型发育性髋关节发育不良(DDH)患者的临床疗效和中期预后。方法:回顾性分析2019年1月至2022年12月在徐州医科大学附属医院行THA治疗的Crowe II/III型DDH患者100例(100髋)。所有患者均行自体股骨头结构骨移植行髋臼重建术。评估围手术期参数、视觉模拟量表(VAS)评分、肢长差异(LLD)、活动范围(ROM)、髋关节功能[Harris髋关节评分和Western Ontario and McMaster university Osteoarthritis Index (WOMAC)]、并发症发生率、生活质量[Generic quality of life Inventory-74 (GQOLI-74)]和影像学结果。结果:平均随访时间为10.78±1.65个月。术后VAS评分由6.52±2.58降至1.73±0.72 (P < 0.001), LLD由2.88±0.54 cm降至0.92±0.39 cm (P < 0.001)。Harris评分由58.23±6.14上升至92.45±5.82 (P < 0.001), WOMAC评分由72.54±8.61下降至18.34±5.09 (P < 0.001)。GQOLI-74评分各领域均有显著改善(P < 0.001)。总并发症发生率为1.0%,x线评估证实骨愈合。结论:THA辅助自体股骨头结构植骨是治疗Crowe II/III型DDH安全有效的方法。它能显著增强髋关节功能,恢复生物力学,改善生活质量,并发症发生率低,中期预后良好。
Clinical efficacy and prognostic analysis of autologous femoral head structural bone grafting combined with total hip arthroplasty for Crowe Type II/III developmental dysplasia of the hip in adults.
Objective: To evaluate the clinical efficacy and mid-term outcomes of total hip arthroplasty (THA) assisted by acetabular reconstruction using autologous femoral head structural bone grafting in patients with Crowe type II/III developmental dysplasia of the hip (DDH).
Methods: A retrospective analysis was conducted on 100 patients (100 hips) with Crowe type II/III DDH who underwent THA at the Affiliated Hospital of Xuzhou Medical University between January 2019 and December 2022. All patients received autologous femoral head structural bone grafting for acetabular reconstruction during the procedure. Perioperative parameters, visual analogue scale (VAS) scores, limb length discrepancy (LLD), range of motion (ROM), hip function [Harris hip score and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)], incidence of complications, quality of life [Generic Quality of Life Inventory-74 (GQOLI-74)], and radiographic outcomes were assessed.
Results: The mean follow-up duration was 10.78 ± 1.65 months. Postoperatively, the VAS score significantly decreased from 6.52 ± 2.58 to 1.73 ± 0.72 (P < 0.001), and the LLD reduced from 2.88 ± 0.54 cm to 0.92 ± 0.39 cm (P < 0.001). The Harris hip score increased from 58.23 ± 6.14 to 92.45 ± 5.82 (P < 0.001), while the WOMAC score decreased from 72.54 ± 8.61 to 18.34 ± 5.09 (P < 0.001). All domains of the GQOLI-74 score showed significant improvements (P < 0.001). The overall complication rate was 1.0%, and radiographic assessments confirmed bone healing.
Conclusion: THA assisted by autologous femoral head structural bone grafting is a safe and effective approach for treating Crowe type II/III DDH. It significantly enhances hip function, restores biomechanics, improves the quality of life, and is associated with a low complication rate and favorable mid-term outcomes.