基于聚4,4 ' -亚甲二苯胺的对乙酰氨基酚分子印迹电化学传感器

IF 2.3 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Journal of the Iranian Chemical Society Pub Date : 2025-08-09 DOI:10.1007/s13738-025-03259-z

Bahareh Hamzeh Khanlou, Mohammad Reza Yaftian, Hassan Shayani-Jam, Farideh Piri

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引用次数: 0

摘要

本文报道了用循环伏安法在玻璃碳电极（GCE）上电聚合4,4′-亚甲苯胺。在接下来的步骤中，利用分子印迹聚合物修饰GCE用于对乙酰氨基酚（ACT）的间接检测。采用六氰高铁酸钾（III）（K3Fe (CN)6）氧化还原探针监测峰值电流的变化。在优化的分析条件下，ACT浓度在0.5 ~ 20mg L - 1范围内呈线性关系，检测限为0.2 mg L - 1。通过血液、安瓿、片剂和牛奶中ACT的测定，验证了传感器的性能，证实了其实用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

An acetaminophen molecularly imprinted electrochemical sensor based a poly 4,4′-methylenedianiline

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An acetaminophen molecularly imprinted electrochemical sensor based a poly 4,4′-methylenedianiline

This study reports the electropolymerization of 4,4′-methylenedianiline on a glassy carbon electrode (GCE) using cyclic voltammetry. In the subsequent step, a molecularly imprinted polymer was employed to modify the GCE for the indirect detection of acetaminophen (ACT). A potassium hexacyanoferrate (III) (K₃Fe (CN)₆) redox probe was utilized to monitor changes in peak current. Under optimized analytical conditions, the ACT concentration exhibited a linear response in the range of 0.5–20 mg L⁻¹, with a detection limit of 0.2 mg L⁻¹. The sensor's performance was successfully validated through the determination of ACT in blood, ampoule, tablets, and milk, confirming its practical applicability.

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来源期刊

Journal of the Iranian Chemical Society 化学-化学综合

CiteScore

4.40

自引率

8.30%

发文量

230

审稿时长

5.6 months

期刊介绍： JICS is an international journal covering general fields of chemistry. JICS welcomes high quality original papers in English dealing with experimental, theoretical and applied research related to all branches of chemistry. These include the fields of analytical, inorganic, organic and physical chemistry as well as the chemical biology area. Review articles discussing specific areas of chemistry of current chemical or biological importance are also published. JICS ensures visibility of your research results to a worldwide audience in science. You are kindly invited to submit your manuscript to the Editor-in-Chief or Regional Editor. All contributions in the form of original papers or short communications will be peer reviewed and published free of charge after acceptance.