采用离子树脂作为可循环电解质,实现了n -杂芳烃与卤苄的氧化还原-中性苄基化反应

IF 8.9 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Yan-Cui Wen , Jia-Cheng Hou , Qian Zhou , Sheng-Hua Wang , Jun Jiang , Zi Yang , Hai-Tao Zhu , Zu-Li Wang , Wei-Min He
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引用次数: 0

摘要

在此,我们开发了一种可持续的线性配对电解策略,用于n -杂芳烃与苄基卤化物的氧化还原-中性苄基化,使用固体离子树脂作为可回收电解质。该方法充分利用阴极和阳极反应制备多种苄基化n -杂芳烃,具有原子经济性和阶梯经济性高、能源效率优异、操作简单、官能团耐受性好、条件温和、不需要牺牲试剂和碱添加剂等特点。重要的是,廉价且可商用的固体离子树脂电解质在克级合成和电解质循环实验中得到了验证。我们希望这一策略不仅为苯基化化合物的可持续合成提供了一种策略,而且也为离子树脂在电合成和线性配对电解中的进一步利用提供了途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Linear paired electrolysis enables redox-neutral benzylation of N-heteroarenes with benzyl halides using ion resin as the recyclable electrolyte

Linear paired electrolysis enables redox-neutral benzylation of N-heteroarenes with benzyl halides using ion resin as the recyclable electrolyte
Herein, we have developed a sustainable linear paired electrolysis strategy for the redox-neutral benzylation of N-heteroarenes with benzyl halides using solid ion resin as the recyclable electrolyte. This method sufficiently utilizes both cathodic and anodic reactions to produce a variety of benzylated N-heteroarenes, features high atom- and step-economy, excellent energy efficiency, operational simplicity, good functional group tolerance, mild conditions and no requirement of sacrifice reagent and base additive. Importantly, the inexpensive and commercially available solid ion resin electrolyte was validated in both gram-scale synthesis and electrolyte cycling experiment. We hope this strategy not only provides a sustainable synthetic strategy for benzylated compounds but also develops the further utilization of ion resin in electrosynthesis as well as linear paired electrolysis.
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来源期刊
Chinese Chemical Letters
Chinese Chemical Letters 化学-化学综合
CiteScore
14.10
自引率
15.40%
发文量
8969
审稿时长
1.6 months
期刊介绍: Chinese Chemical Letters (CCL) (ISSN 1001-8417) was founded in July 1990. The journal publishes preliminary accounts in the whole field of chemistry, including inorganic chemistry, organic chemistry, analytical chemistry, physical chemistry, polymer chemistry, applied chemistry, etc.Chinese Chemical Letters does not accept articles previously published or scheduled to be published. To verify originality, your article may be checked by the originality detection service CrossCheck.
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