{"title":"一种快速共价示踪剂成像应激活细胞中的聚集体。","authors":"Mengdie Wang, Wang Wan, Jialu Sun and Yu Liu","doi":"10.1039/D5CC03014E","DOIUrl":null,"url":null,"abstract":"<p >The commercial PROTEOSTAT aggresome detection kit is not compatible with live-cell applications. Here, we report a rapid covalent fluorescent tracer to visualize aggresomes in stressed live cells without cell fixation.</p>","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":" 84","pages":" 16428-16431"},"PeriodicalIF":4.2000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/cc/d5cc03014e?page=search","citationCount":"0","resultStr":"{\"title\":\"A rapid covalent tracer to image aggresomes in stressed live cells\",\"authors\":\"Mengdie Wang, Wang Wan, Jialu Sun and Yu Liu\",\"doi\":\"10.1039/D5CC03014E\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >The commercial PROTEOSTAT aggresome detection kit is not compatible with live-cell applications. Here, we report a rapid covalent fluorescent tracer to visualize aggresomes in stressed live cells without cell fixation.</p>\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\" 84\",\"pages\":\" 16428-16431\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-09-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://pubs.rsc.org/en/content/articlepdf/2025/cc/d5cc03014e?page=search\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2025/cc/d5cc03014e\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/cc/d5cc03014e","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A rapid covalent tracer to image aggresomes in stressed live cells
The commercial PROTEOSTAT aggresome detection kit is not compatible with live-cell applications. Here, we report a rapid covalent fluorescent tracer to visualize aggresomes in stressed live cells without cell fixation.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.