与年轻人相比,青少年的代谢和减肥手术:MBSAQIP数据库分析。

IF 3.8
Mark Shacker, Stephanie D Chao, Justine O Chinn, Gillian L Fell, Claudia M Mueller, Janey S A Pratt
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引用次数: 0

摘要

背景:代谢和减肥手术(MBS)是一种高度持久、安全、有效的治疗成人严重肥胖的方法。然而,MBS在儿童和青少年人群中仍未得到充分利用,可能是由于儿童择期手术的安全性问题。目的:我们旨在分析与年轻人相比,MBS对青少年的益处是否大于风险。设置:多中心,国家数据库研究。方法:10 ~ 39岁行Roux-en-Y胃旁路术(RYGB)或袖式胃切除术(SG)的患者。既往有前肠手术的患者被排除在外。结果:共发现556628例患者;10-19岁青少年10883人(2.0%),20-29岁青壮年161938人(29.1%),30-39岁成人383807人(69.0%)。术前体重指数(BMI)组间临床差异无统计学意义,但因样本量大,差异有统计学意义(10- 19.46、20- 29.45、30- 39.45 kg/m2, P < 0.001)。SG在年轻人群中更为常见(10- 19.86%,20- 29.77%,30- 39.75%,P < 0.001)。术后30天,青少年BMI下降幅度略大(10-19:2.91,20-29:2.69,30-39:2.53 kg/m2, P < 0.001)。青少年术后并发症较少,包括手术部位感染、胃肠道出血和输血(P < 0.001)。在青少年中,SG (aOR):。39, CI: 0.31 ~ 0.48, P < 0.001)与术后并发症减少相关。结论:接受MBS的青少年的BMI下降与年轻人相似,并发症和再入院率较低。MBS应作为一种安全的治疗方法提供给青少年,以治疗病态肥胖,其频率至少与提供给成年人的频率相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metabolic and bariatric surgery in adolescents compared to young adults: an MBSAQIP database analysis.

Background: Metabolic and bariatric surgery (MBS) is a highly durable, safe and effective treatment for severe obesity in adults. However, MBS remains underutilized in the pediatric and adolescent population, likely due to safety concerns of elective surgery in children.

Objectives: We aimed to analyze whether the benefits of MBS outweigh the risks in adolescents when compared to young adults.

Setting: Multicenter, national database study.

Methods: Patients aged 10-39 who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG). Patients with prior foregut surgery were excluded.

Results: 556,628 patients were identified; 10,883 (2.0%) were aged 10-19 (adolescents), 161,938 (29.1%) were 20-29 (young adults), and 383,807 (69.0%) were 30-39 (adults). Preoperative body mass index (BMI) was clinically similar between groups, though statistically significant due to large sample size (10-19: 46, 20-29: 45, 30-39: 45 kg/m2, P < .001). SG was more common in younger cohorts (10-19: 86%, 20-29: 77%, 30-39: 75%, P < .001). At 30 days postoperatively, adolescents demonstrated marginally greater BMI reduction (10-19: 2.91, 20-29: 2.69, 30-39: 2.53 kg/m2, P < .001). Adolescents had fewer postoperative complications, including surgical site infections, gastrointestinal bleeding, and blood transfusions (P < .001). Among adolescents, SG (aOR: .39, CI: .31-.48, P < .001) was associated with reduced postoperative complications.

Conclusions: Adolescents undergoing MBS have BMI reductions similar to those of young adults and have lower rates of complications and readmissions. MBS should be offered as a safe treatment for adolescents to treat morbid obesity with at least similar frequency as it is offered to adults.

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