寻找完美的匹配：有意识的试验对FMT和纤维治疗溃疡性结肠炎。

IF 11.8 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Med Pub Date : 2025-09-12 DOI:10.1016/j.medj.2025.100842

Lorenza Bartu, Jeremiah J Faith

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引用次数: 0

摘要

每次粪便菌群移植治疗溃疡性结肠炎的试验都会在研讨会和期刊俱乐部引发同样的问题：你能将粪便菌群移植与饮食或纤维结合起来改善菌株植入和结果吗？MINDFUL临床试验通过在27例溃疡性结肠炎患者中测试FMT加或不加车前草纤维的影响来探讨这个问题。

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Searching for the perfect match: MINDFUL trial pairs FMT and fiber for ulcerative colitis.

Every trial of fecal microbiota transplantation for ulcerative colitis inspires the same question at seminars and journal clubs: can you combine FMT with a diet or fiber to improve strain engraftment and outcomes? The MINDFUL clinical trial explores this question by testing the impact of FMT with or without psyllium fiber supplementation in 27 ulcerative colitis patients.

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来源期刊

Med MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

17.70

自引率

0.60%

发文量

102

期刊介绍： Med is a flagship medical journal published monthly by Cell Press, the global publisher of trusted and authoritative science journals including Cell, Cancer Cell, and Cell Reports Medicine. Our mission is to advance clinical research and practice by providing a communication forum for the publication of clinical trial results, innovative observations from longitudinal cohorts, and pioneering discoveries about disease mechanisms. The journal also encourages thought-leadership discussions among biomedical researchers, physicians, and other health scientists and stakeholders. Our goal is to improve health worldwide sustainably and ethically. Med publishes rigorously vetted original research and cutting-edge review and perspective articles on critical health issues globally and regionally. Our research section covers clinical case reports, first-in-human studies, large-scale clinical trials, population-based studies, as well as translational research work with the potential to change the course of medical research and improve clinical practice.