Qian Yan, Mai Zhang, Jie Yao, Zi-Han Zhuang, Shi-Hua Chen, Shi-Hai Yang, Zhi-Wei Li, Jiang-Sheng Li
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Visible-Light-Driven Synthesis of Ester-Substituted Imidazole-Fused Heterocycles via Tandem Radical Cyclization
A novel tandem radical cyclization strategy is reported for the efficient synthesis of ester-functionalized imidazole-fused heterocycles. This method leverages visible-light photocatalysis and modular substrate design to achieve high regioselectivity and atom economy. The protocol demonstrates broad compatibility with diverse N-allylimidazoles and bromoacetates, enabling rapid construction of structurally complex products under mild conditions.
期刊介绍:
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.