60-74岁轻度认知障碍患者的合并症和长期用药分析

IF 3.1 3区医学 Q2 NEUROSCIENCES

Journal of Alzheimer's Disease Pub Date : 2025-09-12 DOI:10.1177/13872877251376674

Andrzej Bożek, Aleksandra Spyra, Natalia Tekiela, Maksymilian Dobosz, Aleksandra Mitka, Martyna Miodońska

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引用次数: 0

摘要

轻度认知障碍（MCI）是一种可能先于阿尔茨海默病发病的疾病。我们感兴趣的是影响MCI诱发的因素。在这项研究中，我们评估了92名MCI患者（年龄60-74岁）和118名对照患者的合并症和用药情况。在轻度认知障碍组中，多重发病的发生率明显更高。轻度认知损伤与年龄、超重、多病、过敏性疾病、抑郁、使用睡眠药物和曲马多衍生物相关。结果表明，在60岁的人群中，MCI的可能性更高，特别是那些患有多种疾病并使用某些类型药物的人群。

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Analysis of comorbidities and chronically used medications in patients with mild cognitive impairment aged 60-74 years.

Mild cognitive impairment (MCI) is a condition that may precede the onset of Alzheimer's disease. Of interest are factors that influence the induction of MCI. In this study, we assessed 92 patients with MCI (aged 60-74 years) and 118 controls for comorbidities and medication. In the MCI group, multimorbidity was observed significantly more often. MCI correlated with age, overweight, multimorbidity, the presence of allergic disease, depression, use of sleep medications and tramadol derivatives. The results indicate a higher possibility of MCI in the 60-year-old group, especially in those with multimorbidity and using certain types of drugs.

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来源期刊

Journal of Alzheimer's Disease 医学-神经科学

CiteScore

6.40

自引率

7.50%

发文量

1327

审稿时长

2 months

期刊介绍： The Journal of Alzheimer''s Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer''s disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer''s disease.