一种新型的环保方法合成具有高抗菌效果的银纳米粒子修饰壳聚糖膜

Q3 Materials Science

JCIS open Pub Date : 2025-09-09 DOI:10.1016/j.jciso.2025.100155

Sri Juari Santosa , Muhammad Hadi , Adhi Dwi Hatmanto , Salwaa Mumtaazah Darmanastri , Eny Kusrini , Khoirina Dwi Nugrahaningtyas , Anwar Usman

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引用次数: 0

摘要

建立了一种新型的环保方法，合成了具有强抗菌活性的超小银纳米颗粒修饰壳聚糖膜。AgNPs是在碱性条件下（pH ~ 12.06）用蔗糖水解得到的葡萄糖在壳聚糖基质中还原AgNO3制备的，以最佳的1:4 Ag+与蔗糖的摩尔比生成球形颗粒（~ 8.6 nm）。将所得的Chit-AgNPs胶体与等体积的甘油混合，制成可生物降解的Chit-AgNPs/G1薄膜，其机械性能符合可生物降解塑料标准。对枯草芽孢杆菌和大肠杆菌的抑菌试验表明，该薄膜的效果明显高于其前体，与标准对照（阿莫西林和倍他定）相当，甚至优于后者。总的来说，chit - agnp /G1薄膜表现出卓越的抗菌性能，使其成为迄今为止报道的最有效的壳聚糖- agnp复合材料之一。

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A novel eco-friendly method for synthesizing silver nanoparticles (AgNPs)-decorated chitosan film having high antibacterial efficacy

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A novel eco-friendly method for synthesizing silver nanoparticles (AgNPs)-decorated chitosan film having high antibacterial efficacy

A novel eco-friendly method was established to synthesize ultra-small silver nanoparticles (AgNPs)-decorated chitosan films with strong antibacterial activity. The AgNPs were produced by reducing AgNO₃ with glucose derived from sucrose hydrolysis under alkaline conditions (pH ∼12.06) in a chitosan matrix, yielding spherical particles (∼8.6 nm) at an optimal 1:4 Ag⁺ to sucrose molar ratio. Mixing the resulting Chit-AgNPs colloid with glycerol in equal volumes produced a biodegradable Chit-AgNPs/G1 film with mechanical properties that meet biodegradable plastic standards. Antibacterial tests against B. subtilis and E. coli revealed that the film exhibited markedly higher efficacy than its precursors and was comparable or even superior to standard controls (amoxicillin and betadine). Overall, the Chit-AgNPs/G1 film demonstrates exceptional antibacterial performance, positioning it as one of the most effective chitosan–AgNP composites reported to date.

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来源期刊

JCIS open Physical and Theoretical Chemistry, Colloid and Surface Chemistry, Surfaces, Coatings and Films

CiteScore

4.10

自引率

0.00%

发文量

审稿时长

36 days