{"title":"纳米技术在生物分析中的应用","authors":"Arshdeep Chopra , Yogindra Kumari , Samarth Kumar , Renuka Sharma , Rohit Bhatia","doi":"10.1016/j.jcoa.2025.100254","DOIUrl":null,"url":null,"abstract":"<div><div>Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade. On the surface, miniaturisation offers mechanical, chemical, and biological components that operate more quickly and affordably. Through the development of new nanoparticles (NPs), nanodevices, nanosensors, and nanosorbents for analytical procedures, the inclusion of nanotechnology has additionally had an impact on bioanalytical sciences. In recent years, numerous studies have been done on the integration of nanomaterials and their analysis in various biological samples. Given the scope of the NPs integrated bioanalysis, the purpose of this review is to provide an overview of multiple types of extraction techniques, sample preparation, and nanomaterials like magnetic NPs, carbon-based NPs, molecularly implanted polymers (MIPs) used in the determination of different drugs in biological specimens, and also to critically evaluate the tools used to examine Green Analytical Chemistry (GAC), such as Green Analytical Procedure Index (GAPI), ComplexGAPI (CoGAPI), Click Analytical Chemistry Index (CACI).</div></div>","PeriodicalId":93576,"journal":{"name":"Journal of chromatography open","volume":"8 ","pages":"Article 100254"},"PeriodicalIF":3.2000,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanotechnology in bioanalysis: Current trends and applications\",\"authors\":\"Arshdeep Chopra , Yogindra Kumari , Samarth Kumar , Renuka Sharma , Rohit Bhatia\",\"doi\":\"10.1016/j.jcoa.2025.100254\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade. On the surface, miniaturisation offers mechanical, chemical, and biological components that operate more quickly and affordably. Through the development of new nanoparticles (NPs), nanodevices, nanosensors, and nanosorbents for analytical procedures, the inclusion of nanotechnology has additionally had an impact on bioanalytical sciences. In recent years, numerous studies have been done on the integration of nanomaterials and their analysis in various biological samples. Given the scope of the NPs integrated bioanalysis, the purpose of this review is to provide an overview of multiple types of extraction techniques, sample preparation, and nanomaterials like magnetic NPs, carbon-based NPs, molecularly implanted polymers (MIPs) used in the determination of different drugs in biological specimens, and also to critically evaluate the tools used to examine Green Analytical Chemistry (GAC), such as Green Analytical Procedure Index (GAPI), ComplexGAPI (CoGAPI), Click Analytical Chemistry Index (CACI).</div></div>\",\"PeriodicalId\":93576,\"journal\":{\"name\":\"Journal of chromatography open\",\"volume\":\"8 \",\"pages\":\"Article 100254\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of chromatography open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772391725000520\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chromatography open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772391725000520","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nanotechnology in bioanalysis: Current trends and applications
Nanotechnology has evolved into an interdisciplinary trend spanning nearly all scientific domains and has had a profound impact on the global community over the last decade. On the surface, miniaturisation offers mechanical, chemical, and biological components that operate more quickly and affordably. Through the development of new nanoparticles (NPs), nanodevices, nanosensors, and nanosorbents for analytical procedures, the inclusion of nanotechnology has additionally had an impact on bioanalytical sciences. In recent years, numerous studies have been done on the integration of nanomaterials and their analysis in various biological samples. Given the scope of the NPs integrated bioanalysis, the purpose of this review is to provide an overview of multiple types of extraction techniques, sample preparation, and nanomaterials like magnetic NPs, carbon-based NPs, molecularly implanted polymers (MIPs) used in the determination of different drugs in biological specimens, and also to critically evaluate the tools used to examine Green Analytical Chemistry (GAC), such as Green Analytical Procedure Index (GAPI), ComplexGAPI (CoGAPI), Click Analytical Chemistry Index (CACI).