液相色谱-质谱耦合用于类固醇激素分析：样品制备和方法开发中的问题和解决方案

IF 3.2

Journal of chromatography open Pub Date : 2025-09-04 DOI:10.1016/j.jcoa.2025.100250

A. Temerdashev , S. Girel , S.N. Atapattu , Y.-Q. Feng , E. Gashimova , T. Malitskaya , I. Podolskiy , Q.-F. Zhu

{"title":"液相色谱-质谱耦合用于类固醇激素分析：样品制备和方法开发中的问题和解决方案","authors":"A. Temerdashev , S. Girel , S.N. Atapattu , Y.-Q. Feng , E. Gashimova , T. Malitskaya , I. Podolskiy , Q.-F. Zhu","doi":"10.1016/j.jcoa.2025.100250","DOIUrl":null,"url":null,"abstract":"<div><div>Current work presents main aspects of the application of liquid chromatography in combination with low- and high-resolution mass spectrometry to an analysis of steroid hormones. Advantages and challenges of both targeted and untargeted analysis are shown together with the most popular approaches to the associated sample preparation. Among emerging approaches, first applications of isotope ratio mass spectrometry in combination with liquid chromatography for the analysis of steroid hormones for doping control purposes are presented and discussed.</div></div>","PeriodicalId":93576,"journal":{"name":"Journal of chromatography open","volume":"8 ","pages":"Article 100250"},"PeriodicalIF":3.2000,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Liquid chromatography coupled to mass spectrometry for steroid hormones analysis: issues and solutions in sample preparation and method development\",\"authors\":\"A. Temerdashev , S. Girel , S.N. Atapattu , Y.-Q. Feng , E. Gashimova , T. Malitskaya , I. Podolskiy , Q.-F. Zhu\",\"doi\":\"10.1016/j.jcoa.2025.100250\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Current work presents main aspects of the application of liquid chromatography in combination with low- and high-resolution mass spectrometry to an analysis of steroid hormones. Advantages and challenges of both targeted and untargeted analysis are shown together with the most popular approaches to the associated sample preparation. Among emerging approaches, first applications of isotope ratio mass spectrometry in combination with liquid chromatography for the analysis of steroid hormones for doping control purposes are presented and discussed.</div></div>\",\"PeriodicalId\":93576,\"journal\":{\"name\":\"Journal of chromatography open\",\"volume\":\"8 \",\"pages\":\"Article 100250\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2025-09-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of chromatography open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772391725000489\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chromatography open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772391725000489","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

目前的工作介绍了液相色谱结合低分辨率和高分辨率质谱分析类固醇激素的主要应用方面。目标分析和非目标分析的优势和挑战，以及最流行的相关样品制备方法。在新兴的方法中，首次应用同位素比质谱法结合液相色谱法分析类固醇激素的兴奋剂控制目的进行了介绍和讨论。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Liquid chromatography coupled to mass spectrometry for steroid hormones analysis: issues and solutions in sample preparation and method development

查看原文本刊更多论文

Liquid chromatography coupled to mass spectrometry for steroid hormones analysis: issues and solutions in sample preparation and method development

Current work presents main aspects of the application of liquid chromatography in combination with low- and high-resolution mass spectrometry to an analysis of steroid hormones. Advantages and challenges of both targeted and untargeted analysis are shown together with the most popular approaches to the associated sample preparation. Among emerging approaches, first applications of isotope ratio mass spectrometry in combination with liquid chromatography for the analysis of steroid hormones for doping control purposes are presented and discussed.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of chromatography open Analytical Chemistry

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

50 days