Synthesis of 3-(1H-benzo[d]imidazole-2-yl)-2-arylthiazolidin-4-one using Fe3O4@SiO2Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu an efficient and magnetically retrievable nanocatalyst

Fe₃O₄@SiO₂Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu were prepared and were analyzed by XRD, FT-IR, VSM, TEM, FE-SEM, and TGA-DTG analysis. These nano catalysts were applied as an efficient and magnetically reusable nanocatalyst for the preparation of various derivatives of thiazolidinones under solvent-free conditions. All of the organic compounds were analyzed by NMR and FT-IR. This avenue offers many benefits, such as productivity, fast reaction, and convenience for work and recovery. The catalyst is reusable for 8 runs by decantation using an efficient magnet without notable loss in activity. This protocol has many advantages, like working better, quickly responding, and making it easy to work. This is the first report to use Fe₃O₄@SiO₂Pr@E-N'-(4-hydroxy-3-methoxybenzylidene) isonicotinohydrazide@Cu to make 3-(1H-benzo[d]imidazole-2-yl)-2-arylthiazolidin-4-ones. The reaction speed is good, and this method works well. The reaction was done without any liquid and in an environmentally friendly and gentle way. The method explained is totally new.