CAR - t细胞受体的人疱疹病毒6病毒血症和脑炎。

IF 23.1 1区医学 Q1 HEMATOLOGY

Blood Pub Date : 2025-09-12 DOI:10.1182/blood.2025029057

Stephanie Teresa Isaac,David C Bishop,Fahad Shaikh,Kenneth P Micklethwaite,David J Gottlieb,Emily Blyth

引用次数: 0

摘要

据报道，在CAR - t细胞受体中HHV-6再激活是罕见的。我们的患者队列（n=119）经历了病毒血症发生率比先前研究高7倍和2例脑炎病例。需要进一步的研究来确定感染的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Human herpesvirus 6 viremia and encephalitis in CAR T-cell recipients.

HHV-6 reactivation in CAR T-cell recipients is reported to be rare. Our patient cohort (n=119) experienced a seven-fold higher incidence of viraemia than a previous study and 2 encephalitis cases. Further studies are needed to determine risk factors for infection.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Blood 医学-血液学

CiteScore

23.60

自引率

3.90%

发文量

955

审稿时长

1 months

期刊介绍： Blood, the official journal of the American Society of Hematology, published online and in print, provides an international forum for the publication of original articles describing basic laboratory, translational, and clinical investigations in hematology. Primary research articles will be published under the following scientific categories: Clinical Trials and Observations; Gene Therapy; Hematopoiesis and Stem Cells; Immunobiology and Immunotherapy scope; Myeloid Neoplasia; Lymphoid Neoplasia; Phagocytes, Granulocytes and Myelopoiesis; Platelets and Thrombopoiesis; Red Cells, Iron and Erythropoiesis; Thrombosis and Hemostasis; Transfusion Medicine; Transplantation; and Vascular Biology. Papers can be listed under more than one category as appropriate.