J Soka, S Mwimanzi, C D Fast, G Mwesiga, N Edward, M Stephen, R Kondo, C Cox, N Beyene, T B Agizew
{"title":"使用训练过的非洲巨袋大鼠作为肺结核临床诊断的预测因子。","authors":"J Soka, S Mwimanzi, C D Fast, G Mwesiga, N Edward, M Stephen, R Kondo, C Cox, N Beyene, T B Agizew","doi":"10.5588/pha.25.0010","DOIUrl":null,"url":null,"abstract":"<p><p>For over a decade, trained African giant pouched rats have been employed in detecting missed pulmonary TB (PTB). However, the relationship between rat-positive results and subsequent clinical PTB or extrapulmonary TB (EPTB) has not been previously reported. This report highlights the use of rat-positivity as a predictor for PTB clinical diagnosis and treatment among presumptive TB. Treating physicians were 1.39 times more likely to clinically diagnose and treat rat-positives than rat-negatives: 12% versus 9%, respectively, odds ratio=1.39, 95% confidence interval: 1.05-1.84<i>.</i> No difference was observed among EPTB.</p>","PeriodicalId":46239,"journal":{"name":"Public Health Action","volume":"15 3","pages":"137-139"},"PeriodicalIF":1.6000,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421851/pdf/","citationCount":"0","resultStr":"{\"title\":\"Use of trained African giant pouched rats as a predictor of clinical diagnosis of pulmonary TB.\",\"authors\":\"J Soka, S Mwimanzi, C D Fast, G Mwesiga, N Edward, M Stephen, R Kondo, C Cox, N Beyene, T B Agizew\",\"doi\":\"10.5588/pha.25.0010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>For over a decade, trained African giant pouched rats have been employed in detecting missed pulmonary TB (PTB). However, the relationship between rat-positive results and subsequent clinical PTB or extrapulmonary TB (EPTB) has not been previously reported. This report highlights the use of rat-positivity as a predictor for PTB clinical diagnosis and treatment among presumptive TB. Treating physicians were 1.39 times more likely to clinically diagnose and treat rat-positives than rat-negatives: 12% versus 9%, respectively, odds ratio=1.39, 95% confidence interval: 1.05-1.84<i>.</i> No difference was observed among EPTB.</p>\",\"PeriodicalId\":46239,\"journal\":{\"name\":\"Public Health Action\",\"volume\":\"15 3\",\"pages\":\"137-139\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-09-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421851/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Public Health Action\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5588/pha.25.0010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Public Health Action","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5588/pha.25.0010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Use of trained African giant pouched rats as a predictor of clinical diagnosis of pulmonary TB.
For over a decade, trained African giant pouched rats have been employed in detecting missed pulmonary TB (PTB). However, the relationship between rat-positive results and subsequent clinical PTB or extrapulmonary TB (EPTB) has not been previously reported. This report highlights the use of rat-positivity as a predictor for PTB clinical diagnosis and treatment among presumptive TB. Treating physicians were 1.39 times more likely to clinically diagnose and treat rat-positives than rat-negatives: 12% versus 9%, respectively, odds ratio=1.39, 95% confidence interval: 1.05-1.84. No difference was observed among EPTB.
期刊介绍:
Launched on 1 May 2011, Public Health Action (PHA) is an official publication of the International Union Against Tuberculosis and Lung Disease (The Union). It is an open access, online journal available world-wide to physicians, health workers, researchers, professors, students and decision-makers, including public health centres, medical, university and pharmaceutical libraries, hospitals, clinics, foundations and institutions. PHA is a peer-reviewed scholarly journal that actively encourages, communicates and reports new knowledge, dialogue and controversy in health systems and services for people in vulnerable and resource-limited communities — all topics that reflect the mission of The Union, Health solutions for the poor.