{"title":"【流式细胞术在骨髓增生异常综合征诊治中的研究进展——综述】。","authors":"Qiu-Cheng Zhang, Bao-An Chen, Jian Cheng","doi":"10.19746/j.cnki.issn.1009-2137.2025.04.044","DOIUrl":null,"url":null,"abstract":"<p><p>Flow cytometry (FCM), as an important method for the diagnosis of acute myeloid leukemia (AML), has been widely used in myelodysplastic syndrome (MDS) in recent years. FCM can effectively identify and characterize abnormal hematopoietic cells through immunophenotyping, particularly in the diagnosis of MDS with insignificant morphological abnormalities. Additionally, FCM can monitor disease progression and minimal residual disease (MRD) by detecting phenotypic changes and evaluate treatment efficacy. This article reviews the latest research progress of FCM in the immunophenotyping, prognosis and efficacy evaluation of MDS.</p>","PeriodicalId":35777,"journal":{"name":"中国实验血液学杂志","volume":"33 4","pages":"1222-1227"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Research Progress of Flow Cytometry in Diagnosis and Treatment of Myelodysplastic Syndrome--Review].\",\"authors\":\"Qiu-Cheng Zhang, Bao-An Chen, Jian Cheng\",\"doi\":\"10.19746/j.cnki.issn.1009-2137.2025.04.044\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Flow cytometry (FCM), as an important method for the diagnosis of acute myeloid leukemia (AML), has been widely used in myelodysplastic syndrome (MDS) in recent years. FCM can effectively identify and characterize abnormal hematopoietic cells through immunophenotyping, particularly in the diagnosis of MDS with insignificant morphological abnormalities. Additionally, FCM can monitor disease progression and minimal residual disease (MRD) by detecting phenotypic changes and evaluate treatment efficacy. This article reviews the latest research progress of FCM in the immunophenotyping, prognosis and efficacy evaluation of MDS.</p>\",\"PeriodicalId\":35777,\"journal\":{\"name\":\"中国实验血液学杂志\",\"volume\":\"33 4\",\"pages\":\"1222-1227\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国实验血液学杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.04.044\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国实验血液学杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.19746/j.cnki.issn.1009-2137.2025.04.044","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
[Research Progress of Flow Cytometry in Diagnosis and Treatment of Myelodysplastic Syndrome--Review].
Flow cytometry (FCM), as an important method for the diagnosis of acute myeloid leukemia (AML), has been widely used in myelodysplastic syndrome (MDS) in recent years. FCM can effectively identify and characterize abnormal hematopoietic cells through immunophenotyping, particularly in the diagnosis of MDS with insignificant morphological abnormalities. Additionally, FCM can monitor disease progression and minimal residual disease (MRD) by detecting phenotypic changes and evaluate treatment efficacy. This article reviews the latest research progress of FCM in the immunophenotyping, prognosis and efficacy evaluation of MDS.